Showing entry for Sn1-specific diacylglycerol lipase alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022274
Protein NameSn1-specific diacylglycerol lipase alpha
Uniport IdQ9Y4D2
GeneDAGLA
Gene Id747
DomainLipase_3
Pfam PF01764  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.6 Nervous system hsa04723 Retrograde endocannabinoid signaling
5. Organismal Systems 5.2 Endocrine system hsa04925 Aldosterone synthesis and secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019369 arachidonic acid metabolic process
Biological Process GO:0046340 diacylglycerol catabolic process
Biological Process GO:0071926 endocannabinoid signaling pathway
Biological Process GO:0007216 G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0007405 neuroblast proliferation
Biological Process GO:0022008 neurogenesis
Biological Process GO:0042136 neurotransmitter biosynthetic process
Biological Process GO:0150077 regulation of neuroinflammatory response
Biological Process GO:0098921 retrograde trans-synaptic signaling by endocannabinoid
molecular function GO:0016787 hydrolase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0032590 dendrite membrane
cellular component GO:0032591 dendritic spine membrane
cellular component GO:0031901 early endosome membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0043196 varicosity
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114508 Effects of PIP2 hydrolysis
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-426048 Arachidonate production from DAG
R-HSA-76002 Platelet activation, signaling and aggregation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0042834 BXGD003004 Vital capacity
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0202177 BXGD004079 Phospholipid measurement
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234251 BXGD004645 Inflammatory pain Pathological Conditions, Signs and Symptoms
C0342788 BXGD007552 Renal carnitine transport defect Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C0523465 BXGD009209 Serum albumin measurement
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1519383 BXGD013237 Smoking Behaviors Behavior and Behavior Mechanisms
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C2699541 BXGD017461 Cytokine Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0009122 Zein 174.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein