Showing entry for Sorting nexin-10


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022305
Protein NameSorting nexin-10
Uniport IdQ9Y5X0
GeneSNX10
Gene Id29887
DomainPX
Pfam PF00787  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035630 bone mineralization involved in bone maturation
Biological Process GO:0045453 bone resorption
Biological Process GO:0055074 calcium ion homeostasis
Biological Process GO:1990830 cellular response to leukemia inhibitory factor
Biological Process GO:0060271 cilium assembly
Biological Process GO:0006897 endocytosis
Biological Process GO:0007032 endosome organization
Biological Process GO:0001696 gastric acid secretion
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0030316 osteoclast differentiation
Biological Process GO:0071539 protein localization to centrosome
Biological Process GO:0061512 protein localization to cilium
Biological Process GO:0097178 ruffle assembly
Biological Process GO:0044691 tooth eruption
molecular function GO:0005545 1-phosphatidylinositol binding
molecular function GO:0051117 ATPase binding
cellular component GO:0090651 apical cytoplasm
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0031313 extrinsic component of endosome membrane
cellular component GO:0005815 microtubule organizing center
cellular component GO:0005634 nucleus
cellular component GO:0030141 secretory granule
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003578 BXGD000211 Apnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008711 BXGD000566 Chronic rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0015469 BXGD000996 Facial paralysis Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Stomatognathic Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020598 BXGD001440 Hypocalcemia Nutritional and Metabolic Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029454 BXGD002155 Osteopetrosis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029882 BXGD002177 Otitis Media Otorhinolaryngologic Diseases
C0030232 BXGD002197 Pallor Pathological Conditions, Signs and Symptoms
C0035579 BXGD002560 Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085682 BXGD003238 Hypophosphatemia Nutritional and Metabolic Diseases
C0151311 BXGD003412 Cranial nerve palsies Nervous System Diseases
C0151825 BXGD003481 Bone pain Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205682 BXGD004105 Waist-Hip Ratio
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0232466 BXGD004543 Feeding difficulties
C0238397 BXGD004923 Pulmonary artery stenosis Cardiovascular Diseases
C0239174 BXGD004969 Late tooth eruption
C0242567 BXGD005177 Opsoclonus Eye Diseases; Nervous System Diseases
C0266052 BXGD005614 Precocious exfoliation of primary tooth Stomatognathic Diseases
C0271344 BXGD006187 Compression of optic nerve Eye Diseases; Nervous System Diseases
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0392885 BXGD008071 High density lipoprotein measurement
C0423798 BXGD008510 Increased tendency to bruise Wounds and Injuries
C0426790 BXGD008577 Narrow thorax
C0456070 BXGD008863 Growth delay
C0497156 BXGD009053 Lymphadenopathy Hemic and Lymphatic Diseases
C0522214 BXGD009196 Abnormal visual evoked potential Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1318518 BXGD012396 Infantile malignant osteopetrosis Musculoskeletal Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1519383 BXGD013237 Smoking Behaviors Behavior and Behavior Mechanisms
C1832160 BXGD013803 Abnormality of temperature regulation
C1842083 BXGD014494 Abnormality of the ribs
C1855340 BXGD015490 Bowing of the long bones
C1963077 BXGD016680 Bone Pain, CTCAE 3.0
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C2132198 BXGD016930 Abnormal blistering of the skin
C2674432 BXGD017246 Reduced bone mineral density
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3164374 BXGD018527 Abnormality of pulmonary valve
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3554478 BXGD019217 OSTEOPETROSIS, AUTOSOMAL RECESSIVE 8
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3805574 BXGD019481 Increased fracture rate
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C4021611 BXGD020697 Abnormality of epiphysis morphology
C4023722 BXGD021253 Abnormality of hair texture
C4025814 BXGD021806 Abnormality of the metaphysis
C4272578 BXGD022330 Autosomal Recessive Osteopetrosis Musculoskeletal Diseases
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4554063 BXGD023559 Bone Pain, CTCAE 5.0
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002722 Nitrate 62
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein