Showing entry for Mitochondrial ornithine transporter 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022316
Protein NameMitochondrial ornithine transporter 1
Uniport IdQ9Y619
GeneSLC25A15
Gene Id10166
DomainMito_carr
Pfam PF00153  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990575 mitochondrial L-ornithine transmembrane transport
Biological Process GO:0000050 urea cycle
molecular function GO:0000064 L-ornithine transmembrane transporter activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005743 mitochondrial inner membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-70635 Urea cycle
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002064 BXGD000100 Alkalosis, Respiratory Nutritional and Metabolic Diseases; Respiratory Tract Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0009024 BXGD000578 Clonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0009421 BXGD000608 Comatose Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0009676 BXGD000619 Confusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023380 BXGD001640 Lethargy Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0026499 BXGD001905 Monosomy Pathological Conditions, Signs and Symptoms
C0027651 BXGD002009 Neoplasms Neoplasms
C0037771 BXGD002702 Paraparesis, Spastic Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037772 BXGD002703 Spastic Paraplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0151891 BXGD003499 Retinal depigmentation Pathological Conditions, Signs and Symptoms; Eye Diseases; Skin and Connective Tissue Diseases
C0154246 BXGD003709 Urea Cycle Disorders, Inborn Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0220994 BXGD004357 Hyperammonemia Pathological Conditions, Signs and Symptoms
C0231687 BXGD004509 Spastic gait Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0231835 BXGD004527 Tachypnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0232466 BXGD004543 Feeding difficulties
C0232744 BXGD004561 Decreased liver function
C0234132 BXGD004623 Pyramidal sign Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0264611 BXGD005403 Apraxia of Phonation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0267797 BXGD005777 Acute hepatitis Digestive System Diseases
C0268128 BXGD005828 Orotic aciduria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0268540 BXGD005976 HHH syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268542 BXGD005977 Ornithine carbamoyltransferase deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0393525 BXGD008081 Progressive cerebellar ataxia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0424230 BXGD008522 Motor retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0557874 BXGD009444 Global developmental delay
C0563243 BXGD009479 Poor coordination Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0599035 BXGD009675 Hyperornithinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1295585 BXGD012241 Decreased vibratory sense Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1306587 BXGD012368 Acute encephalopathy Nervous System Diseases
C1739135 BXGD013733 Progression of prostate cancer
C1833434 BXGD013925 Multifocal cerebral white matter abnormalities Pathological Conditions, Signs and Symptoms
C1838993 BXGD014351 Episodic vomiting Pathological Conditions, Signs and Symptoms
C1839531 BXGD014381 Protein avoidance
C1848701 BXGD014967 Elevated hepatic transaminase
C1857640 BXGD015726 Decreased nerve conduction velocity
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4021759 BXGD020762 Generalized myoclonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4021761 BXGD020763 Morphological abnormality of the pyramidal tract
C4022483 BXGD020904 Chorioretinal hypopigmentation
C4022738 BXGD020974 Neurodevelopmental delay
C4025790 BXGD021791 Specific learning disability
C4048273 BXGD021898 Chorioretinal atrophy Eye Diseases
C4551583 BXGD023361 Cerebral cortical atrophy
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0052927 Ornithine 132.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein