Showing entry for Cysteine desulfurase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022322
Protein NameCysteine desulfurase, mitochondrial
Uniport IdQ9Y697
GeneNFS1
Gene Id9054
DomainAminotran_5
Pfam PF00266  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00730 Thiamine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04122 Sulfur relay system
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0018283 iron incorporation into metallo-sulfur cluster
Biological Process GO:0016226 iron-sulfur cluster assembly
Biological Process GO:0032324 molybdopterin cofactor biosynthetic process
Biological Process GO:0006777 Mo-molybdopterin cofactor biosynthetic process
Biological Process GO:0044281 small molecule metabolic process
molecular function GO:0031071 cysteine desulfurase activity
molecular function GO:0051536 iron-sulfur cluster binding
molecular function GO:0046872 metal ion binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0030170 pyridoxal phosphate binding
cellular component GO:0005829 cytosol
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Biological Process GO:0044571 2Fe-2S cluster assembly
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0394005 BXGD008165 Ataxic cerebral palsy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0431129 BXGD008665 Adamantinous Craniopharyngioma Neoplasms
C0919677 BXGD011435 Protein C measurement
C1168438 BXGD011793 Protein C antigen measurement
C4750855 BXGD024077 Severe neonatal lactic acidosis due to NFS1-ISD11 complex deficiency Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000279 L-Alanine 89.09
BXGC0000436 Glycerol 92.09
BXGC0006271 L-Cysteine 121.16
BXGC0030612 tetraethylene glycol 194.12
BXGC0043088 Pyridoxal Phosphate 247.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein