Showing entry for Epsin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022330
Protein NameEpsin-1
Uniport IdQ9Y6I3
GeneEPN1
Gene Id29924
DomainENTH
Pfam PF01417  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048568 embryonic organ development
Biological Process GO:0006897 endocytosis
Biological Process GO:0007565 female pregnancy
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0061024 membrane organization
Biological Process GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
Biological Process GO:1903671 negative regulation of sprouting angiogenesis
Biological Process GO:0007219 Notch signaling pathway
molecular function GO:0030276 clathrin binding
molecular function GO:0005543 phospholipid binding
cellular component GO:0005905 clathrin-coated pit
cellular component GO:0030125 clathrin vesicle coat
cellular component GO:0005829 cytosol
cellular component GO:0005768 endosome
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-177929 Signaling by EGFR
R-HSA-182971 EGFR downregulation
R-HSA-199991 Membrane Trafficking
R-HSA-5653656 Vesicle-mediated transport
R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis
R-HSA-8856828 Clathrin-mediated endocytosis
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0740392 BXGD009988 Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042315 1,4-dioxane 88.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein