Showing entry for Lymphocyte antigen 96


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022346
Protein NameLymphocyte antigen 96
Uniport IdQ9Y6Y9
GeneLY96
Gene Id23643
Domain-
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04064 NF-kappa B signaling pathway
5. Organismal Systems 5.1 Immune system hsa04620 Toll-like receptor signaling pathway
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05130 Pathogenic Escherichia coli infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05133 Pertussis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05145 Toxoplasmosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097190 apoptotic signaling pathway
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0006968 cellular defense response
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0032497 detection of lipopolysaccharide
Biological Process GO:0007249 I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0006954 inflammatory response
Biological Process GO:0045087 innate immune response
Biological Process GO:0002755 MyD88-dependent toll-like receptor signaling pathway
Biological Process GO:0002756 MyD88-independent toll-like receptor signaling pathway
Biological Process GO:0070266 necroptotic process
Biological Process GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway
Biological Process GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
Biological Process GO:0032760 positive regulation of tumor necrosis factor production
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0034142 toll-like receptor 4 signaling pathway
Biological Process GO:0002224 toll-like receptor signaling pathway
Biological Process GO:0035666 TRIF-dependent toll-like receptor signaling pathway
molecular function GO:0015026 coreceptor activity
molecular function GO:0001530 lipopolysaccharide binding
molecular function GO:0001875 lipopolysaccharide immune receptor activity
molecular function GO:0035662 Toll-like receptor 4 binding
cellular component GO:0010008 endosome membrane
cellular component GO:0005615 extracellular space
cellular component GO:0031226 intrinsic component of plasma membrane
cellular component GO:0046696 lipopolysaccharide receptor complex
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-109581 Apoptosis
R-HSA-1236974 ER-Phagosome pathway
R-HSA-1236975 Antigen processing-Cross presentation
R-HSA-1280218 Adaptive Immune System
R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand
R-HSA-1643685 Disease
R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane
R-HSA-166166 MyD88-independent TLR4 cascade
R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade
R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade
R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168898 Toll-like Receptor Cascades
R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade
R-HSA-2562578 TRIF-mediated programmed cell death
R-HSA-5260271 Diseases of Immune System
R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway
R-HSA-5357801 Programmed Cell Death
R-HSA-5602358 Diseases associated with the TLR signaling cascade
R-HSA-5602498 MyD88 deficiency (TLR2/4)
R-HSA-5603041 IRAK4 deficiency (TLR2/4)
R-HSA-5686938 Regulation of TLR by endogenous ligand
R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
R-HSA-937041 IKK complex recruitment mediated by RIP1
R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling
R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex
R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
R-HSA-975155 MyD88 dependent cascade initiated on endosome
R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
R-HSA-983169 Class I MHC mediated antigen processing & presentation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0007097 BXGD000424 Carcinoma Neoplasms
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0041296 BXGD002903 Tuberculosis Infections
C0042029 BXGD002951 Urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0042109 BXGD002957 Urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0205696 BXGD004107 Anaplastic carcinoma Neoplasms
C0205697 BXGD004108 Carcinoma, Spindle-Cell Neoplasms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0205699 BXGD004110 Carcinomatosis Neoplasms
C0206695 BXGD004246 Carcinoma, Neuroendocrine Neoplasms
C0221232 BXGD004413 Welts Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0242966 BXGD005201 Systemic Inflammatory Response Syndrome Pathological Conditions, Signs and Symptoms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262655 BXGD005264 Recurrent urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0267375 BXGD005742 Chronic colitis Digestive System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0393814 BXGD008149 Hereditary liability to pressure palsies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0747845 BXGD010184 early pregnancy
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3662483 BXGD019270 Allergic sensitization
C3714514 BXGD019409 Infection Infections
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C4082937 BXGD022095 Necrotizing enterocolitis in fetus OR newborn Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002144 Tetradecanoic acid 228.37
BXGC0002248 Dodecanoic acid 200.32
BXGC0002906 Caffeic acid ester 284.31
BXGC0005982 Curcumin 368.38
BXGC0008873 Xanthohumol 354.4
BXGC0026326 (R)-3-Hydroxymyristic acid 244.2
BXGC0030901 Morphine 285.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein