Showing entry for Replicase polyprotein 1ab


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022392
Protein NameReplicase polyprotein 1ab
Uniport IdQ9YN02
Generep
Gene Id
Domain-
Pfam PF16749   PF14757   PF14756   PF05410   PF05411   PF05412   PF05579   PF00680   PF01443  
OrganismPorcine reproductive and respiratory syndrome virus (strain 16244B) (PRRSV)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0039648 modulation by virus of host protein ubiquitination
Biological Process GO:0039579 suppression by virus of host ISG15 activity
Biological Process GO:0039644 suppression by virus of host NF-kappaB transcription factor activity
Biological Process GO:0039563 suppression by virus of host STAT1 activity
Biological Process GO:0039502 suppression by virus of host type I interferon-mediated signaling pathway
Biological Process GO:0006351 transcription, DNA-templated
Biological Process GO:0019082 viral protein processing
Biological Process GO:0039694 viral RNA genome replication
molecular function GO:0005524 ATP binding
molecular function GO:0004197 cysteine-type endopeptidase activity
molecular function GO:0003678 DNA helicase activity
molecular function GO:0003723 RNA binding
molecular function GO:0003968 RNA-directed 5'-3' RNA polymerase activity
molecular function GO:0003724 RNA helicase activity
molecular function GO:0004252 serine-type endopeptidase activity
molecular function GO:0036459 thiol-dependent ubiquitinyl hydrolase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0033644 host cell membrane
cellular component GO:0042025 host cell nucleus
cellular component GO:0044220 host cell perinuclear region of cytoplasm
cellular component GO:0016021 integral component of membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein