Showing entry for Gamma-aminobutyric acid type B receptor subunit 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022401
Protein NameGamma-aminobutyric acid type B receptor subunit 1
Uniport IdQ9Z0U4
GeneGabbr1
Gene Id81657
Domain7tm_3; ANF_receptor; Sushi
Pfam PF00003   PF01094   PF00084  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0007214 gamma-aminobutyric acid signaling pathway
Biological Process GO:0007194 negative regulation of adenylate cyclase activity
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0033602 negative regulation of dopamine secretion
Biological Process GO:0032811 negative regulation of epinephrine secretion
Biological Process GO:0014053 negative regulation of gamma-aminobutyric acid secretion
Biological Process GO:0050805 negative regulation of synaptic transmission
Biological Process GO:0150099 neuron-glial cell signaling
Biological Process GO:0001649 osteoblast differentiation
Biological Process GO:0014049 positive regulation of glutamate secretion
Biological Process GO:0060124 positive regulation of growth hormone secretion
Biological Process GO:0014048 regulation of glutamate secretion
Biological Process GO:0045471 response to ethanol
Biological Process GO:0035094 response to nicotine
molecular function GO:1990430 extracellular matrix protein binding
molecular function GO:0004965 G protein-coupled GABA receptor activity
molecular function GO:0099579 G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0008134 transcription factor binding
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0030673 axolemma
cellular component GO:0005737 cytoplasm
cellular component GO:0043198 dendritic shaft
cellular component GO:0043197 dendritic spine
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005615 extracellular space
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:1902710 GABA receptor complex
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0038037 G protein-coupled receptor dimeric complex
cellular component GO:0038039 G protein-coupled receptor heterodimeric complex
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0031966 mitochondrial membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0043204 perikaryon
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0098793 presynapse
cellular component GO:0042734 presynaptic membrane
cellular component GO:0098685 Schaffer collateral - CA1 synapse
cellular component GO:0097060 synaptic membrane
cellular component GO:0008021 synaptic vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001626 3-Aminopropanoic acid 89.09
BXGC0002867 Lappaurin 284.74
BXGC0003196 Aripiprazole 448.39
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0005995 Imidazole 68.08
BXGC0030085 Bicuculline 367.11
BXGC0039168 phosphorylethanolamine 141.02
BXGC0039350 Gs-39783 337.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein