protein

Showing entry for NF-kappa-B inhibitor alpha

General Target Information
BXGT Id	BXGT022404
Protein Name	NF-kappa-B inhibitor alpha
Uniport Id	Q9Z1E3
Gene	Nfkbia
Gene Id	18035
Domain	Ank_2
Pfam	PF00023 PF12796
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0071345	cellular response to cytokine stimulus
Biological Process	GO:0071407	cellular response to organic cyclic compound
Biological Process	GO:0071356	cellular response to tumor necrosis factor
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB
Biological Process	GO:0042994	cytoplasmic sequestering of transcription factor
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway
Biological Process	GO:0010888	negative regulation of lipid storage
Biological Process	GO:0010745	negative regulation of macrophage derived foam cell differentiation
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity
Biological Process	GO:0045746	negative regulation of Notch signaling pathway
Biological Process	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway
Biological Process	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
Biological Process	GO:0032270	positive regulation of cellular protein metabolic process
Biological Process	GO:0010875	positive regulation of cholesterol efflux
Biological Process	GO:0050729	positive regulation of inflammatory response
Biological Process	GO:0045893	positive regulation of transcription, DNA-templated
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
Biological Process	GO:0006606	protein import into nucleus
Biological Process	GO:0042127	regulation of cell population proliferation
Biological Process	GO:0010468	regulation of gene expression
Biological Process	GO:0043330	response to exogenous dsRNA
Biological Process	GO:0032496	response to lipopolysaccharide
Biological Process	GO:0032495	response to muramyl dipeptide
Biological Process	GO:0035994	response to muscle stretch
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway
molecular function	GO:0019899	enzyme binding
molecular function	GO:0031072	heat shock protein binding
molecular function	GO:0042802	identical protein binding
molecular function	GO:0051059	NF-kappaB binding
molecular function	GO:0008139	nuclear localization sequence binding
molecular function	GO:0044877	protein-containing complex binding
molecular function	GO:0031625	ubiquitin protein ligase binding
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005829	cytosol
cellular component	GO:0005634	nucleus
cellular component	GO:0005886	plasma membrane
cellular component	GO:0032991	protein-containing complex

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0001024	Cirsimaritin		314.29
BXGC0011627	Glycyrrhetic acid		470.69
BXGC0025215	Lupeol		426.39

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}