Showing entry for STE20/SPS1-related proline-alanine-rich protein kinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022408
Protein NameSTE20/SPS1-related proline-alanine-rich protein kinase
Uniport IdQ9Z1W9
GeneStk39
Gene Id53416
DomainOSR1_C; Pkinase
Pfam PF12202   PF00069  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0071476 cellular hypotonic response
Biological Process GO:1990869 cellular response to chemokine
Biological Process GO:0038146 chemokine (C-X-C motif) ligand 12 signaling pathway
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0050801 ion homeostasis
Biological Process GO:0036438 maintenance of lens transparency
Biological Process GO:1905408 negative regulation of creatine transmembrane transporter activity
Biological Process GO:0090188 negative regulation of pancreatic juice secretion
Biological Process GO:1901380 negative regulation of potassium ion transmembrane transport
Biological Process GO:1901017 negative regulation of potassium ion transmembrane transporter activity
Biological Process GO:2000650 negative regulation of sodium ion transmembrane transporter activity
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0032414 positive regulation of ion transmembrane transporter activity
Biological Process GO:0043268 positive regulation of potassium ion transport
Biological Process GO:0010820 positive regulation of T cell chemotaxis
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0023014 signal transduction by protein phosphorylation
Biological Process GO:0023016 signal transduction by trans-phosphorylation
molecular function GO:0005524 ATP binding
molecular function GO:0016301 kinase activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0019898 extrinsic component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein