Showing entry for Kelch-like ECH-associated protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022415
Protein NameKelch-like ECH-associated protein 1
Uniport IdQ9Z2X8
GeneKeap1
Gene Id50868
DomainBACK; BTB; Kelch_1
Pfam PF07707   PF00651   PF01344  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071322 cellular response to carbohydrate stimulus
Biological Process GO:0071353 cellular response to interleukin-4
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0042994 cytoplasmic sequestering of transcription factor
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0010506 regulation of autophagy
Biological Process GO:0045604 regulation of epidermal cell differentiation
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0097718 disordered domain specific binding
molecular function GO:0042802 identical protein binding
molecular function GO:0008134 transcription factor binding
cellular component GO:0005884 actin filament
cellular component GO:0005912 adherens junction
cellular component GO:0034451 centriolar satellite
cellular component GO:0031463 Cul3-RING ubiquitin ligase complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005925 focal adhesion
cellular component GO:0016234 inclusion body
cellular component GO:0030496 midbody
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0003705 Chloride 35.45
BXGC0004576 2-tert-Butyl-1,4-benzenediol 166.22
BXGC0006216 Sulforaphane 177.29
BXGC0006368 Formic acid 46.03
BXGC0029784 Fumaric Acid 116.01
BXGC0045224 (3E,4R,5S)-4-hydroxy-5-methyl-3-tetradecylidene-oxolan-2-one 310.25
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein