Showing entry for Sodium-coupled neutral amino acid transporter 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022646
Protein NameSodium-coupled neutral amino acid transporter 1
Uniport IdQ9H2H9
GeneSLC38A1
Gene Id81539
Domain_trans
Pfam PF01490  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.6 Nervous system hsa04724 Glutamatergic synapse
5. Organismal Systems 5.6 Nervous system hsa04727 GABAergic synapse
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0003333 amino acid transmembrane transport
Biological Process GO:0006865 amino acid transport
Biological Process GO:0006868 glutamine transport
Biological Process GO:1902475 L-alpha-amino acid transmembrane transport
Biological Process GO:0001504 neurotransmitter uptake
Biological Process GO:0015804 neutral amino acid transport
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0005283 amino acid:sodium symporter activity
molecular function GO:0015171 amino acid transmembrane transporter activity
molecular function GO:0015179 L-amino acid transmembrane transporter activity
molecular function GO:0015186 L-glutamine transmembrane transporter activity
molecular function GO:0005295 neutral amino acid:sodium symporter activity
molecular function GO:0015175 neutral amino acid transmembrane transporter activity
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0098591 external side of apical plasma membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-112313 Neurotransmitter uptake and metabolism In glial cells
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-210455 Astrocytic Glutamate-Glutamine Uptake And Metabolism
R-HSA-352230 Amino acid transport across the plasma membrane
R-HSA-382551 Transport of small molecules
R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
R-HSA-425407 SLC-mediated transmembrane transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0005612 BXGD000317 Birth Weight Pathological Conditions, Signs and Symptoms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007120 BXGD000435 Bronchioloalveolar Adenocarcinoma Neoplasms
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0017636 BXGD001131 Glioblastoma Neoplasms
C0020500 BXGD001408 Hyperoxaluria Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034951 BXGD002498 Refractive Errors Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0206702 BXGD004252 Klatskin Tumor Neoplasms
C0220726 BXGD004333 Diastrophic dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0236734 BXGD004823 Caffeine related disorders
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0438696 BXGD008805 Suicidal Behavior and Behavior Mechanisms
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1827820 BXGD013778 Fast acetylator due to N-acetyltransferase enzyme variant
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2825864 BXGD017778 Antithrombin Antigen Measurement
C3472608 BXGD018921 Micropapillary carcinoma
C3853540 BXGD019820 Aspirin exacerbated respiratory disease Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases; Immune System Diseases; Chemically-Induced Disorders; Otorhinolaryngologic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000458 L-Asparagine 132.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein