Showing entry for Voltage-dependent calcium channel gamma-3 subunit


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022652
Protein NameVoltage-dependent calcium channel gamma-3 subunit
Uniport IdO60359
GeneCACNG3
Gene Id10368
DomainPMP22_Claudin
Pfam PF00822  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
5. Organismal Systems 5.3 Circulatory system hsa04260 Cardiac muscle contraction
5. Organismal Systems 5.3 Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes
5. Organismal Systems 5.2 Endocrine system hsa04921 Oxytocin signaling pathway
6. Human Diseases 6.6 Cardiovascular diseases hsa05410 Hypertrophic cardiomyopathy (HCM)
6. Human Diseases 6.6 Cardiovascular diseases hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
6. Human Diseases 6.6 Cardiovascular diseases hsa05414 Dilated cardiomyopathy (DCM)
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0061337 cardiac conduction
Biological Process GO:0099590 neurotransmitter receptor internalization
Biological Process GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome
Biological Process GO:2000969 positive regulation of AMPA receptor activity
Biological Process GO:0051968 positive regulation of synaptic transmission, glutamatergic
Biological Process GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping
Biological Process GO:0008104 protein localization
Biological Process GO:0006605 protein targeting
Biological Process GO:2000311 regulation of AMPA receptor activity
Biological Process GO:0019226 transmission of nerve impulse
molecular function GO:0016247 channel regulator activity
molecular function GO:0035255 ionotropic glutamate receptor binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0005245 voltage-gated calcium channel activity
cellular component GO:0032281 AMPA glutamate receptor complex
cellular component GO:0030425 dendrite
cellular component GO:0030666 endocytic vesicle membrane
cellular component GO:0060076 excitatory synapse
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0098685 Schaffer collateral - CA1 synapse
cellular component GO:0036477 somatodendritic compartment
cellular component GO:0005891 voltage-gated calcium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-1266738 Developmental Biology
R-HSA-399719 Trafficking of AMPA receptors
R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity
R-HSA-5682910 LGI-ADAM interactions
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0014553 BXGD000931 Absence Epilepsy Nervous System Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C1305855 BXGD012348 Body mass index
C4281785 BXGD022415 Childhood Absence Epilepsy Nervous System Diseases
C4552000 BXGD023473 Episodic Kinesigenic Dyskinesia 1 Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003611 Latex 416.57
BXGC0006372 Ergocalciferol 396.65
BXGC0024988 Nifedipine 346.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein