Showing entry for Elongation of very long chain fatty acids protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022660
Protein NameElongation of very long chain fatty acids protein 2
Uniport IdQ9NXB9
GeneELOVL2
Gene Id54898
DomainELO
Pfam PF01151  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00062 Fatty acid elongation
1. Metabolism 1.3 Lipid metabolism hsa01040 Biosynthesis of unsaturated fatty acids
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
1. Metabolism 1.0 Global and overview maps hsa01212 Fatty acid metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0036109 alpha-linolenic acid metabolic process
Biological Process GO:0034625 fatty acid elongation, monounsaturated fatty acid
Biological Process GO:0034626 fatty acid elongation, polyunsaturated fatty acid
Biological Process GO:0019367 fatty acid elongation, saturated fatty acid
Biological Process GO:0043651 linoleic acid metabolic process
Biological Process GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
Biological Process GO:0030148 sphingolipid biosynthetic process
Biological Process GO:0006636 unsaturated fatty acid biosynthetic process
Biological Process GO:0042761 very long-chain fatty acid biosynthetic process
molecular function GO:0102336 3-oxo-arachidoyl-CoA synthase activity
molecular function GO:0102337 3-oxo-cerotoyl-CoA synthase activity
molecular function GO:0102338 3-oxo-lignoceronyl-CoA synthase activity
molecular function GO:0009922 fatty acid elongase activity
molecular function GO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0030176 integral component of endoplasmic reticulum membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
R-HSA-2046105 Linoleic acid (LA) metabolism
R-HSA-2046106 alpha-linolenic acid (ALA) metabolism
R-HSA-556833 Metabolism of lipids
R-HSA-75105 Fatty acyl-CoA biosynthesis
R-HSA-75876 Synthesis of very long-chain fatty acyl-CoAs
R-HSA-8978868 Fatty acid metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0202177 BXGD004079 Phospholipid measurement
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0337438 BXGD007159 Glucose measurement
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0495706 BXGD009038 elevated blood glucose level
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0848676 BXGD010883 Subfertility, Male Male Urogenital Diseases
C0869220 BXGD011305 Adverse effects, not elsewhere classified
C0917731 BXGD011407 Male sterility Male Urogenital Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C1281901 BXGD012133 Fatty acid measurement
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1611184 BXGD013455 Calcification of coronary artery Nutritional and Metabolic Diseases; Cardiovascular Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006107 alpha-Linolenic acid 278.43
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein