Showing entry for Diacylglycerol kinase gamma


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022669
Protein NameDiacylglycerol kinase gamma
Uniport IdP49619
GeneDGKG
Gene Id1608
DomainC1_1; DAGK_acc; DAGK_cat; DAG_kinase_N
Pfam PF00130   PF14513   PF00609   PF00781  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00561 Glycerolipid metabolism
1. Metabolism 1.3 Lipid metabolism hsa00564 Glycerophospholipid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04070 Phosphatidylinositol signaling system
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
6. Human Diseases 6.1 Cancers: Overview hsa05231 Choline metabolism in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046339 diacylglycerol metabolic process
Biological Process GO:0046486 glycerolipid metabolic process
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0046834 lipid phosphorylation
Biological Process GO:0090038 negative regulation of protein kinase C signaling
Biological Process GO:0048666 neuron development
Biological Process GO:0006654 phosphatidic acid biosynthetic process
Biological Process GO:0030168 platelet activation
Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0050773 regulation of dendrite development
molecular function GO:0005524 ATP binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0004143 diacylglycerol kinase activity
molecular function GO:0008289 lipid binding
molecular function GO:0003951 NAD+ kinase activity
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114508 Effects of PIP2 hydrolysis
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-76002 Platelet activation, signaling and aggregation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005893 BXGD000346 Body mass index procedure
C0005910 BXGD000349 Body Weight Pathological Conditions, Signs and Symptoms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0016529 BXGD001068 Forced expiratory volume function
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042109 BXGD002957 Urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C0221232 BXGD004413 Welts Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0338508 BXGD007196 Optic Atrophy 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Nervous System Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0455829 BXGD008859 Waist Circumference
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0562350 BXGD009476 Hip circumference
C0578022 BXGD009541 Finding of body mass index
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0679427 BXGD009777 myeloblastosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1305855 BXGD012348 Body mass index
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4049938 BXGD021956 Physical Activity Measurement
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0037274 (+)-Alpha-Tocopheryl Succinate 530.4
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein