Showing entry for Diacylglycerol kinase kappa


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022671
Protein NameDiacylglycerol kinase kappa
Uniport IdQ5KSL6
GeneDGKK
Gene Id139189
DomainC1_1; DAGK_acc; DAGK_cat; PH
Pfam PF00130   PF00609   PF00781   PF00169  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00561 Glycerolipid metabolism
1. Metabolism 1.3 Lipid metabolism hsa00564 Glycerophospholipid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04070 Phosphatidylinositol signaling system
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
6. Human Diseases 6.1 Cancers: Overview hsa05231 Choline metabolism in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046339 diacylglycerol metabolic process
Biological Process GO:0046486 glycerolipid metabolic process
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0046834 lipid phosphorylation
Biological Process GO:0030168 platelet activation
Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0006979 response to oxidative stress
molecular function GO:0005524 ATP binding
molecular function GO:0004143 diacylglycerol kinase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0003951 NAD+ kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114508 Effects of PIP2 hydrolysis
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-76002 Platelet activation, signaling and aggregation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0004930 BXGD000294 Behavior Disorders Mental Disorders
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0016667 BXGD001072 Fragile X Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1691215 BXGD013491 Penile hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0037274 (+)-Alpha-Tocopheryl Succinate 530.4
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein