Showing entry for Calpain-8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022690
Protein NameCalpain-8
Uniport IdA6NHC0
GeneCAPN8
Gene Id388743
DomainCalpain_III; Peptidase_C2
Pfam PF01067   PF00648  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007586 digestion
Biological Process GO:0006508 proteolysis
molecular function GO:0005509 calcium ion binding
molecular function GO:0016787 hydrolase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005794 Golgi apparatus
Reactome
Pathway Id Pathway Name
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474244 Extracellular matrix organization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0027877 BXGD002055 Neuronal Ceroid-Lipofuscinoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0085078 BXGD003118 Lysosomal Storage Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0751383 BXGD010422 Juvenile Neuronal Ceroid Lipofuscinosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein