Showing entry for Merlin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022767
Protein NameMerlin
Uniport IdP46662
GeneNf2
Gene Id18016
DomainERM; FERM_C; FERM_M; FERM_N
Pfam PF00769   PF09380   PF00373   PF09379  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0007420 brain development
Biological Process GO:0045216 cell-cell junction organization
Biological Process GO:0007398 ectoderm development
Biological Process GO:0021766 hippocampus development
Biological Process GO:0070306 lens fiber cell differentiation
Biological Process GO:0001707 mesoderm formation
Biological Process GO:0022408 negative regulation of cell-cell adhesion
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0043409 negative regulation of MAPK cascade
Biological Process GO:0006469 negative regulation of protein kinase activity
Biological Process GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
Biological Process GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0042475 odontogenesis of dentin-containing tooth
Biological Process GO:0045597 positive regulation of cell differentiation
Biological Process GO:0051496 positive regulation of stress fiber assembly
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0014013 regulation of gliogenesis
Biological Process GO:0035330 regulation of hippo signaling
Biological Process GO:2000177 regulation of neural precursor cell proliferation
Biological Process GO:0050767 regulation of neurogenesis
Biological Process GO:1900180 regulation of protein localization to nucleus
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:0072091 regulation of stem cell proliferation
Biological Process GO:0014010 Schwann cell proliferation
molecular function GO:0003779 actin binding
molecular function GO:0008013 beta-catenin binding
molecular function GO:0005178 integrin binding
molecular function GO:0019904 protein domain specific binding
cellular component GO:0005912 adherens junction
cellular component GO:0045177 apical part of cell
cellular component GO:0044297 cell body
cellular component GO:0032154 cleavage furrow
cellular component GO:0030864 cortical actin cytoskeleton
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0030175 filopodium
cellular component GO:0030027 lamellipodium
cellular component GO:0045121 membrane raft
cellular component GO:0043005 neuron projection
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0001726 ruffle
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein