Showing entry for DNA topoisomerase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022830
Protein NameDNA topoisomerase 1
Uniport IdP06612
GenetopA
Gene Id48135422;945862
DomainTopoisom_bac; Topo_Zn_Ribbon; Toprim; zf-C4_Topoisom
Pfam PF08272   PF01131   PF01751   PF01396  
OrganismEscherichia coli (strain K12)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006265 DNA topological change
molecular function GO:0003677 DNA binding
molecular function GO:0003916 DNA topoisomerase activity
molecular function GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005694 chromosome
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein