Showing entry for Protein timeless homolog


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022882
Protein NameProtein timeless homolog
Uniport IdQ9UNS1
GeneTIMELESS
Gene Id8914
DomainTIMELESS; TIMELESS_C
Pfam PF04821   PF05029  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048754 branching morphogenesis of an epithelial tube
Biological Process GO:0044770 cell cycle phase transition
Biological Process GO:0051301 cell division
Biological Process GO:1904976 cellular response to bleomycin
Biological Process GO:0072719 cellular response to cisplatin
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0072711 cellular response to hydroxyurea
Biological Process GO:0007623 circadian rhythm
Biological Process GO:0009582 detection of abiotic stimulus
Biological Process GO:0006281 DNA repair
Biological Process GO:0006260 DNA replication
Biological Process GO:0000076 DNA replication checkpoint
Biological Process GO:0030324 lung development
Biological Process GO:0002009 morphogenesis of an epithelium
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:2000781 positive regulation of double-strand break repair
Biological Process GO:1905168 positive regulation of double-strand break repair via homologous recombination
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0043111 replication fork arrest
Biological Process GO:0048478 replication fork protection
molecular function GO:0003677 DNA binding
cellular component GO:0000790 nuclear chromatin
cellular component GO:0000228 nuclear chromosome
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0031298 replication fork protection complex
cellular component GO:0035861 site of double-strand break
Reactome
Pathway Id Pathway Name
R-HSA-5693532 DNA Double-Strand Break Repair
R-HSA-5693538 Homology Directed Repair
R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
R-HSA-5693607 Processing of DNA double-strand break ends
R-HSA-73894 DNA Repair
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002382 BXGD000109 Alveolar Bone Loss Musculoskeletal Diseases; Stomatognathic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0011311 BXGD000714 Dengue Fever Infections
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014057 BXGD000880 Japanese Encephalitis Infections; Nervous System Diseases
C0014457 BXGD000915 Eosinophilia Hemic and Lymphatic Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0017638 BXGD001132 Glioma Neoplasms
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020651 BXGD001460 Hypotension, Orthostatic Nervous System Diseases; Cardiovascular Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024530 BXGD001783 Malaria Infections
C0024534 BXGD001784 Malaria, Cerebral Infections; Nervous System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0032231 BXGD002339 Pleurisy Infections; Respiratory Tract Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0034152 BXGD002467 Henoch-Schoenlein Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0041296 BXGD002903 Tuberculosis Infections
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042769 BXGD002999 Virus Diseases Infections
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0162557 BXGD003956 Liver Failure, Acute Digestive System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242917 BXGD005200 Filoviridae Infections Infections
C0264408 BXGD005387 Childhood asthma Respiratory Tract Diseases; Immune System Diseases
C0268314 BXGD005895 Cholestasis-edema syndrome, Norwegian type Digestive System Diseases; Hemic and Lymphatic Diseases
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280803 BXGD006766 Primary central nervous system lymphoma Neoplasms; Immune System Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0282687 BXGD006826 Hemorrhagic Fever, Ebola Infections
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333307 BXGD006946 Superficial ulcer Pathological Conditions, Signs and Symptoms
C0333983 BXGD006975 Hyperplastic Polyp Pathological Conditions, Signs and Symptoms
C0338831 BXGD007216 Manic Mental Disorders
C0340164 BXGD007305 Lofgrens syndrome Hemic and Lymphatic Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0398650 BXGD008212 Immune thrombocytopenic purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0403416 BXGD008282 Idiopathic crescentic glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0429494 BXGD008653 Ocular axial length
C0521158 BXGD009130 Recurrent tumor
C0523465 BXGD009209 Serum albumin measurement
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0541798 BXGD009263 Early Awakening Nervous System Diseases; Mental Disorders
C0581874 BXGD009573 Late insomnia Nervous System Diseases; Mental Disorders
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0694549 BXGD009851 Community acquired pneumonia Infections; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0700201 BXGD009880 Dyssomnias Nervous System Diseases; Mental Disorders
C0744421 BXGD010095 Immune-complex glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0748355 BXGD010195 Acute respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0752304 BXGD010711 Hypoxic-Ischemic Encephalopathy Nervous System Diseases; Cardiovascular Diseases
C0796074 BXGD010793 MOHR-TRANEBJAERG SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Mental Disorders; Otorhinolaryngologic Diseases; Behavior and Behavior Mechanisms
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0853193 BXGD010968 Bipolar I disorder Mental Disorders
C0854739 BXGD011027 Advanced sleep phase
C0859021 BXGD011201 Hyperthymic state
C0860027 BXGD011211 Leishmania infantum disease
C0917801 BXGD011412 Sleeplessness Nervous System Diseases; Mental Disorders
C0919747 BXGD011439 Cytokine storm
C0947785 BXGD011495 [D]Sleep disturbances (& [hypersomnia] or [insomnia])
C0947961 BXGD011498 Atopic disorders
C0948216 BXGD011517 Ovarian adenocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1276071 BXGD012103 Childhood atopic dermatitis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306759 BXGD012374 Eosinophilic disorder Hemic and Lymphatic Diseases
C1332629 BXGD012540 Breast Fibrocystic Change, Proliferative Type Skin and Connective Tissue Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1827849 BXGD013780 IgE-mediated allergic asthma Immune System Diseases
C1855179 BXGD015468 CATARACT, ANTERIOR POLAR Eye Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2699541 BXGD017461 Cytokine Measurement
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3539781 BXGD019086 Progressive cGVHD
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3825816 BXGD019704 Pneumonia in children
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887524 BXGD019892 Skin Erosion Skin and Connective Tissue Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329 BXGD021904 Immunosuppression
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein