Showing entry for Neuroblastoma suppressor of tumorigenicity 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022908
Protein NameNeuroblastoma suppressor of tumorigenicity 1
Uniport IdP41271
GeneNBL1
Gene Id100532736;4681
DomainDAN
Pfam PF03045  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04350 TGF-beta signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009887 animal organ morphogenesis
Biological Process GO:0048263 determination of dorsal identity
Biological Process GO:0030514 negative regulation of BMP signaling pathway
Biological Process GO:0090027 negative regulation of monocyte chemotaxis
Biological Process GO:0007399 nervous system development
Biological Process GO:0048812 neuron projection morphogenesis
Biological Process GO:0045666 positive regulation of neuron differentiation
Biological Process GO:0038098 sequestering of BMP from receptor via BMP binding
Biological Process GO:0035582 sequestering of BMP in extracellular matrix
molecular function GO:0036122 BMP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0016015 morphogen activity
molecular function GO:0048018 receptor ligand activity
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005890 BXGD000345 Body Height
C0005956 BXGD000356 Bone Marrow Diseases Hemic and Lymphatic Diseases
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0021167 BXGD001487 Incontinence Nervous System Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0151526 BXGD003432 Premature Birth Female Urogenital Diseases and Pregnancy Complications
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205682 BXGD004105 Waist-Hip Ratio
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0268238 BXGD005862 Triglyceride storage disease with ichthyosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0278694 BXGD006564 Disseminated neuroblastoma Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0751783 BXGD010592 Lafora Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1135161 BXGD011690 Stage 4S neuroblastoma
C1269955 BXGD012005 Tumor Cell Invasion
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2242456 BXGD016972 thyroid function
C2985280 BXGD018223 Blood Protein Measurement
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4722306 BXGD023798 Metastatic Neuroblastoma Neoplasms
C4725671 BXGD023833 High-Risk Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein