Showing entry for Merlin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022927
Protein NameMerlin
Uniport IdP35240
GeneNF2
Gene Id4771
DomainERM; FERM_C; FERM_M; FERM_N
Pfam PF00769   PF09380   PF00373   PF09379  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04392 Hippo signaling pathway - multiple species
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0045216 cell-cell junction organization
Biological Process GO:0007398 ectoderm development
Biological Process GO:0021766 hippocampus development
Biological Process GO:0070306 lens fiber cell differentiation
Biological Process GO:0001707 mesoderm formation
Biological Process GO:0022408 negative regulation of cell-cell adhesion
Biological Process GO:0001953 negative regulation of cell-matrix adhesion
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0043409 negative regulation of MAPK cascade
Biological Process GO:0006469 negative regulation of protein kinase activity
Biological Process GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
Biological Process GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0042475 odontogenesis of dentin-containing tooth
Biological Process GO:0045597 positive regulation of cell differentiation
Biological Process GO:0051496 positive regulation of stress fiber assembly
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0014013 regulation of gliogenesis
Biological Process GO:0035330 regulation of hippo signaling
Biological Process GO:2000177 regulation of neural precursor cell proliferation
Biological Process GO:1900180 regulation of protein localization to nucleus
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:0072091 regulation of stem cell proliferation
Biological Process GO:0014010 Schwann cell proliferation
molecular function GO:0003779 actin binding
cellular component GO:0005912 adherens junction
cellular component GO:0045177 apical part of cell
cellular component GO:0044297 cell body
cellular component GO:0032154 cleavage furrow
cellular component GO:0030864 cortical actin cytoskeleton
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0031527 filopodium membrane
cellular component GO:0030027 lamellipodium
cellular component GO:0016020 membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-5627123 RHO GTPases activate PAKs
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002453 BXGD000117 Amenorrhea Pathological Conditions, Signs and Symptoms
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004604 BXGD000278 Back Pain Pathological Conditions, Signs and Symptoms
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007370 BXGD000462 Catalepsy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010038 BXGD000643 Corneal Opacity Eye Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013264 BXGD000808 Muscular Dystrophy, Duchenne Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0013456 BXGD000843 Earache Pathological Conditions, Signs and Symptoms; Otorhinolaryngologic Diseases
C0014474 BXGD000917 Ependymoma Neoplasms
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0015393 BXGD000981 Eye Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0015469 BXGD000996 Facial paralysis Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Stomatognathic Diseases
C0017525 BXGD001112 Giant Cell Tumors Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018681 BXGD001214 Headache Pathological Conditions, Signs and Symptoms
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018922 BXGD001247 hemangiopericytoma Neoplasms
C0018989 BXGD001263 Hemiparesis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019340 BXGD001321 Herpes NOS Infections
C0019562 BXGD001336 Von Hippel-Lindau Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021125 BXGD001483 Impulsive Behavior Behavior and Behavior Mechanisms
C0021171 BXGD001488 Bloch Sulzberger syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026499 BXGD001905 Monosomy Pathological Conditions, Signs and Symptoms
C0027498 BXGD001994 Nausea and vomiting Pathological Conditions, Signs and Symptoms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027708 BXGD002025 Nephroblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027766 BXGD002034 Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0027809 BXGD002040 Neurilemmoma Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027830 BXGD002046 neurofibroma Neoplasms; Nervous System Diseases
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0027832 BXGD002048 Neurofibromatosis 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0027859 BXGD002052 Acoustic Neuroma Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0028047 BXGD002067 Nicotine withdrawal Chemically-Induced Disorders; Mental Disorders
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028866 BXGD002094 Oculomotor Nerve Paralysis Eye Diseases; Nervous System Diseases
C0028945 BXGD002099 oligodendroglioma Neoplasms
C0029089 BXGD002107 Ophthalmoplegia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029882 BXGD002177 Otitis Media Otorhinolaryngologic Diseases
C0030353 BXGD002213 Papilledema Eye Diseases; Nervous System Diseases
C0032229 BXGD002337 Pleural Neoplasms Neoplasms; Respiratory Tract Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037268 BXGD002675 Skin Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037930 BXGD002714 Spinal Cord Neoplasms Neoplasms; Nervous System Diseases
C0039070 BXGD002787 Syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0040264 BXGD002857 Tinnitus Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0040411 BXGD002859 Tongue Neoplasms Neoplasms; Stomatognathic Diseases
C0040997 BXGD002894 Trigeminal Neuralgia Nervous System Diseases; Stomatognathic Diseases
C0042024 BXGD002949 Urinary Incontinence Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042571 BXGD002991 Vertigo Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0085136 BXGD003131 Central Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0085390 BXGD003160 Li-Fraumeni Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases
C0085633 BXGD003216 Mood swings Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0086543 BXGD003294 Cataract Eye Diseases
C0086692 BXGD003306 Benign Neoplasm Neoplasms
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0151313 BXGD003413 Sensory neuropathy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151740 BXGD003468 Intracranial Hypertension Nervous System Diseases
C0151811 BXGD003478 Subcutaneous nodule Neoplasms; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0152025 BXGD003521 Polyneuropathy Nervous System Diseases
C0153579 BXGD003668 Malignant neoplasm of fallopian tube Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0154671 BXGD003726 Degenerative brain disorder Nervous System Diseases
C0162678 BXGD003974 Neurofibromatoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205834 BXGD004131 Meningiomas, Multiple Neoplasms; Nervous System Diseases
C0205945 BXGD004142 Sarcoma, Spindle Cell Neoplasms
C0206727 BXGD004272 Nerve Sheath Tumors Neoplasms; Nervous System Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0220695 BXGD004323 Neurofibromatosis, type 4, of Riccardi Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0220998 BXGD004359 Hypothalamic hypothyroidism Endocrine System Diseases
C0221184 BXGD004402 Bitemporal Hemianopia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0234144 BXGD004625 Dysgraphia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236734 BXGD004823 Caffeine related disorders
C0238122 BXGD004882 Fallopian Tube Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0241011 BXGD005073 Low serum estradiol levels
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0242350 BXGD005154 Erectile dysfunction Male Urogenital Diseases; Mental Disorders
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0259785 BXGD005222 Malignant Meningioma Neoplasms; Nervous System Diseases
C0260037 BXGD005227 Multiple tumors Neoplasms
C0262576 BXGD005255 Nerve paralysis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0265325 BXGD005516 Turcot syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nervous System Diseases
C0270680 BXGD006083 Posterior fossa compression syndrome
C0270921 BXGD006133 Axonal neuropathy Nervous System Diseases
C0271623 BXGD006222 Hypogonadotropic hypogonadism Endocrine System Diseases
C0272285 BXGD006336 Heparin-induced thrombocytopenia Hemic and Lymphatic Diseases
C0278152 BXGD006503 Hemifacial Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Stomatognathic Diseases
C0278488 BXGD006515 Carcinoma breast stage IV
C0278689 BXGD006563 Recurrent ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0278874 BXGD006605 Adult Ependymoma Neoplasms
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281784 BXGD006785 Benign Meningioma Neoplasms; Nervous System Diseases
C0311394 BXGD006884 Difficulty walking Pathological Conditions, Signs and Symptoms
C0332563 BXGD006894 Papule Pathological Conditions, Signs and Symptoms
C0334605 BXGD007133 Meningothelial meningioma Neoplasms; Nervous System Diseases
C0334606 BXGD007134 Fibrous Meningioma Neoplasms; Nervous System Diseases
C0334607 BXGD007135 Psammomatous Meningioma Neoplasms; Nervous System Diseases
C0334608 BXGD007136 Angiomatous Meningioma Neoplasms; Nervous System Diseases
C0334609 BXGD007137 Hemangioblastic Meningioma Neoplasms; Nervous System Diseases
C0334610 BXGD007138 Hemangiopericytic Meningioma Neoplasms; Nervous System Diseases
C0334611 BXGD007139 Transitional Meningioma Neoplasms; Nervous System Diseases
C0338591 BXGD007204 Amnesia, Transient Global Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0339543 BXGD007267 Epiretinal Membrane Eye Diseases
C0342422 BXGD007479 Pituitary gland enlarged Nervous System Diseases; Endocrine System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0346109 BXGD007779 Malignant Mesothelioma of Peritoneum Neoplasms; Respiratory Tract Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0347515 BXGD007858 Spinal Meningioma Neoplasms; Nervous System Diseases
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0349582 BXGD007932 Trigeminal schwannoma Neoplasms
C0349604 BXGD007934 Intracranial Meningioma Neoplasms; Nervous System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0431121 BXGD008661 Clear Cell Meningioma Neoplasms; Nervous System Diseases
C0431380 BXGD008680 Cortical Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0456909 BXGD008883 Blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0457190 BXGD008886 Xanthomatous Meningioma Neoplasms; Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0476122 BXGD008978 ovarian serous tumor
C0476405 BXGD008993 Lung function testing abnormal
C0496899 BXGD009046 Benign neoplasm of brain, unspecified Neoplasms; Nervous System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0544886 BXGD009319 Somatic mutation
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0575081 BXGD009512 Gait abnormality Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677776 BXGD009728 Hereditary Breast and Ovarian Cancer Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0694563 BXGD009854 Excessive daytime somnolence
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0751303 BXGD010385 Cerebral Convexity Meningioma Neoplasms; Nervous System Diseases
C0751304 BXGD010386 Parasagittal Meningioma Neoplasms; Nervous System Diseases
C0751396 BXGD010425 Well Differentiated Oligodendroglioma Neoplasms
C0751495 BXGD010473 Seizures, Focal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751691 BXGD010554 Perineurioma Neoplasms; Nervous System Diseases
C0795878 BXGD010757 Monosomy 22 Pathological Conditions, Signs and Symptoms
C0796611 BXGD010835 Newly Diagnosed Childhood Ependymoma Neoplasms
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0917817 BXGD011420 Neurofibromatosis 3 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1136041 BXGD011704 Familial Acoustic Neuroma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1136042 BXGD011705 Neuroma, Acoustic, Bilateral Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1136043 BXGD011706 Schwannoma, Acoustic, Bilateral Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1266042 BXGD011938 Chromophobe Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1266043 BXGD011939 Sarcomatoid Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1266044 BXGD011940 Collecting Duct Carcinoma of the Kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1266184 BXGD011991 Atypical Teratoid Rhabdoid Tumor Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1300127 BXGD012268 Perivascular Epithelioid Cell Neoplasms Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306837 BXGD012377 Papillary Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1333015 BXGD012581 Childhood Kidney Wilms Tumor Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1333600 BXGD012636 Hereditary Malignant Neoplasm Neoplasms
C1333989 BXGD012669 Familial meningioma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C1334261 BXGD012691 Intraorbital Meningioma Neoplasms; Nervous System Diseases
C1334271 BXGD012693 Intraventricular Meningioma Neoplasms; Nervous System Diseases
C1334957 BXGD012747 Neoplasm of the posterior pituitary Neoplasms; Nervous System Diseases; Endocrine System Diseases
C1335107 BXGD012760 Olfactory Groove Meningioma Neoplasms; Nervous System Diseases
C1335929 BXGD012814 Schwannomatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases; Nervous System Diseases
C1377610 BXGD012924 Peritoneal Mesothelioma Digestive System Diseases; Neoplasms
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1384406 BXGD012937 Secretory meningioma Neoplasms; Nervous System Diseases
C1384408 BXGD012938 Microcystic meningioma Neoplasms; Nervous System Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1519353 BXGD013236 Skin Papule Skin and Connective Tissue Diseases
C1527197 BXGD013259 Angioblastic Meningioma Neoplasms; Nervous System Diseases
C1527349 BXGD013277 Ductal Breast Carcinoma Neoplasms
C1527390 BXGD013285 Neoplasms, Intracranial Neoplasms; Nervous System Diseases
C1565950 BXGD013406 Posterior Fossa Meningioma Neoplasms; Nervous System Diseases
C1565951 BXGD013407 Sphenoid Wing Meningioma Neoplasms; Nervous System Diseases
C1608408 BXGD013434 Malignant transformation
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1698196 BXGD013513 Muscle Weakness Upper Limb Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1827293 BXGD013768 Carcinoma of urinary bladder, invasive Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1836296 BXGD014105 Muscle Weakness Lower Limb Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1836623 BXGD014139 Decreased circulating cortisol level Immune System Diseases; Endocrine System Diseases
C1842981 BXGD014547 NEUROTICISM Behavior and Behavior Mechanisms
C1849570 BXGD015067 Progressive pulmonary function impairment Respiratory Tract Diseases
C1851584 BXGD015221 Childhood Ependymoma Neoplasms
C1853141 BXGD015307 Slow decrease in visual acuity
C1853554 BXGD015342 Radiation induced meningioma Neoplasms; Nervous System Diseases; Wounds and Injuries
C1859436 BXGD015888 Weak extraocular muscles Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C1860253 BXGD015974 Pseudoepiphyses of the metacarpals
C1861403 BXGD016045 Variable expressivity
C1861975 BXGD016095 Cafe au lait spots, multiple Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1863408 BXGD016177 Juvenile posterior subcapsular lenticular opacities
C1863653 BXGD016186 Unilateral vestibular Schwannoma Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1866129 BXGD016375 Abnormality of the cerebellum Nervous System Diseases
C1959582 BXGD016636 PTEN Hamartoma Tumor Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2919945 BXGD017882 Cavernous Hemangioma of Brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C2931480 BXGD018027 Neurofibromatosis, Type 3, mixed central and peripheral Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C2937358 BXGD018159 Cerebral Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2945759 BXGD018189 aggressive cancer
C3163622 BXGD018514 Papillary Meningioma Neoplasms; Nervous System Diseases
C3272425 BXGD018622 Gastric Schwannoma
C3280492 BXGD018831 TUMOR PREDISPOSITION SYNDROME
C3495917 BXGD019012 Advanced breast cancer
C3551915 BXGD019148 MENINGIOMA, FAMILIAL, SUSCEPTIBILITY TO
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3665349 BXGD019280 Secondary hypothyroidism Endocrine System Diseases
C3810474 BXGD019659 Occasional neurofibromas Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C4017083 BXGD020399 SCHWANNOMATOSIS, SOMATIC
C4021206 BXGD020578 Chromosomal breakage induced by ionizing radiation Pathological Conditions, Signs and Symptoms
C4021655 BXGD020723 Abnormality of the sense of smell
C4021789 BXGD020781 Abnormality of the vertebral column
C4021850 BXGD020819 Increased sensitivity to ionizing radiation
C4022395 BXGD020896 Abnormality of the mediastinum
C4022775 BXGD020998 Focal T2 hypointense thalamic lesion
C4022798 BXGD021001 Abnormal brain FDG positron emission tomography
C4023205 BXGD021143 Neoplasm of the anterior pituitary Neoplasms; Nervous System Diseases; Endocrine System Diseases
C4023215 BXGD021147 Abnormality of central sensory function
C4024276 BXGD021315 Peripheral Schwannoma Neoplasms; Skin and Connective Tissue Diseases
C4024716 BXGD021383 Secondary growth hormone deficiency
C4025669 BXGD021720 Decreased circulating ACTH level
C4048809 BXGD021910 SCHWANNOMATOSIS 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases; Nervous System Diseases
C4054534 BXGD021982 Meningioangiomatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C4072889 BXGD022012 Decreased circulating follicle stimulating hormone level
C4072890 BXGD022013 Decreased circulating luteinizing hormone level
C4073006 BXGD022032 Visual acuity test abnormality
C4073063 BXGD022034 Abnormal kinetic perimetry test
C4073137 BXGD022045 Decreased serum testosterone level
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4284013 BXGD022428 Primary cholangiocarcinoma of intrahepatic biliary tract Neoplasms
C4288754 BXGD022484 Metastatic urothelial carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4551915 BXGD023441 Gait Disturbance, CTCAE
C4552960 BXGD023530 Ear Pain, CTCAE
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4733092 BXGD023907 estrogen receptor-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein