Showing entry for C-C motif chemokine 16


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023188
Protein NameC-C motif chemokine 16
Uniport IdO15467
GeneCCL16
Gene Id6360
DomainIL8
Pfam PF00048  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor
5. Organismal Systems 5.1 Immune system hsa04062 Chemokine signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0007154 cell communication
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0071347 cellular response to interleukin-1
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0070098 chemokine-mediated signaling pathway
Biological Process GO:0006935 chemotaxis
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0006954 inflammatory response
Biological Process GO:0048247 lymphocyte chemotaxis
Biological Process GO:0002548 monocyte chemotaxis
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0043547 positive regulation of GTPase activity
molecular function GO:0048020 CCR chemokine receptor binding
molecular function GO:0042056 chemoattractant activity
molecular function GO:0008009 chemokine activity
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-380108 Chemokine receptors bind chemokines
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034068 BXGD002457 Pulmonary Eosinophilia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0086543 BXGD003294 Cataract Eye Diseases
C0206368 BXGD004176 Exfoliation Syndrome Eye Diseases
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0220654 BXGD004311 Meningeal Carcinomatosis Neoplasms; Nervous System Diseases
C0221505 BXGD004466 Lesion of brain
C0302332 BXGD006841 Poisoning syndrome
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0339573 BXGD007271 Glaucoma, Primary Open Angle Eye Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1527407 BXGD013291 Eosinophilic Pneumonia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein