Showing entry for DNA annealing helicase and endonuclease ZRANB3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023211
Protein NameDNA annealing helicase and endonuclease ZRANB3
Uniport IdQ5FWF4
GeneZRANB3
Gene Id84083
DomainHelicase_C; HNH; SNF2_N; zf-RanBP
Pfam PF00271   PF01844   PF00176   PF00641  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0032508 DNA duplex unwinding
Biological Process GO:0006281 DNA repair
Biological Process GO:0036292 DNA rewinding
Biological Process GO:0045910 negative regulation of DNA recombination
Biological Process GO:0031297 replication fork processing
Biological Process GO:0048478 replication fork protection
Biological Process GO:0009411 response to UV
molecular function GO:0036310 annealing helicase activity
molecular function GO:0005524 ATP binding
molecular function GO:0008094 DNA-dependent ATPase activity
molecular function GO:0004520 endodeoxyribonuclease activity
molecular function GO:0004386 helicase activity
molecular function GO:0070530 K63-linked polyubiquitin modification-dependent protein binding
molecular function GO:0046872 metal ion binding
cellular component GO:0043596 nuclear replication fork
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0009691 BXGD000622 Congenital cataract Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Nervous System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085298 BXGD003155 Sudden Cardiac Death Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0266544 BXGD005691 Microcornea Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0423224 BXGD008475 Sunken eyes Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0557874 BXGD009444 Global developmental delay
C0562350 BXGD009476 Hip circumference
C0877024 BXGD011330 Schimke immunoosseous dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Respiratory Tract Diseases; Immune System Diseases; Cardiovascular Diseases
C0948379 BXGD011533 Impaired insulin secretion
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1838625 BXGD014327 Warburg Sjo Fledelius syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein