Showing entry for m7GpppN-mRNA hydrolase



                       
General Target Information
BXGT IdBXGT023326
Protein Namem7GpppN-mRNA hydrolase
Uniport IdQ8IU60
GeneDCP2
Gene Id167227
DomainDCP2; NUDIX
Pfam PF05026   PF00293  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa03018 RNA degradation
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
Biological Process GO:0043928 exonucleolytic catabolism of deadenylated mRNA
Biological Process GO:0071044 histone mRNA catabolic process
Biological Process GO:0006402 mRNA catabolic process
Biological Process GO:0032211 negative regulation of telomere maintenance via telomerase
Biological Process GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Biological Process GO:0043488 regulation of mRNA stability
Biological Process GO:1904872 regulation of telomerase RNA localization to Cajal body
molecular function GO:0004534 5'-3' exoribonuclease activity
molecular function GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters
molecular function GO:0050072 m7G(5')pppN diphosphatase activity
molecular function GO:0030145 manganese ion binding
molecular function GO:0070034 telomerase RNA binding
cellular component GO:0030054 cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0036464 cytoplasmic ribonucleoprotein granule
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0000932 P-body
cellular component GO:0016442 RISC complex
Reactome
Pathway Id Pathway Name
R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress
R-HSA-381042 PERK regulates gene expression
R-HSA-381119 Unfolded Protein Response (UPR)
R-HSA-392499 Metabolism of proteins
R-HSA-429914 Deadenylation-dependent mRNA decay
R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease
R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements
R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0045008 Oprea1_783471 247.12
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein