Showing entry for KN motif and ankyrin repeat domain-containing protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023544
Protein NameKN motif and ankyrin repeat domain-containing protein 2
Uniport IdQ63ZY3
GeneKANK2
Gene Id25959
DomainAnk_2; KN_motif
Pfam PF12796   PF12075  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0090521 glomerular visceral epithelial cell migration
Biological Process GO:0072073 kidney epithelium development
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
Biological Process GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
Biological Process GO:0043069 negative regulation of programmed cell death
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0070563 negative regulation of vitamin D receptor signaling pathway
Biological Process GO:0035023 regulation of Rho protein signal transduction
cellular component GO:0005737 cytoplasm
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007125 BXGD000438 Carcinoma, Ehrlich Tumor Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011633 BXGD000742 Dermatomyositis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020445 BXGD001386 Hypercholesterolemia, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0022579 BXGD001558 Keratoderma Skin and Connective Tissue Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0033687 BXGD002415 Proteinuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0042345 BXGD002977 Varicosity Cardiovascular Diseases
C0152424 BXGD003588 Common ventricle Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0206161 BXGD004167 Reticulocyte count (procedure)
C0221056 BXGD004383 Adult type dermatomyositis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0240182 BXGD005023 Leukonychia Skin and Connective Tissue Diseases
C0270549 BXGD006079 Generalized Anxiety Disorder Mental Disorders
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0427460 BXGD008616 Red cell distribution width determination
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0871470 BXGD011316 Systolic Pressure
C1135196 BXGD011694 Heart Failure, Diastolic Cardiovascular Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1445957 BXGD013081 Serum total cholesterol measurement
C1843300 BXGD014572 Sparse eyelashes
C1857042 BXGD015669 Sparse scalp hair
C1862863 BXGD016138 Sparse body hair
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3274516 BXGD018654 Single Ventricle Defect
C3890602 BXGD020024 Bodily Pain Pathological Conditions, Signs and Symptoms
C4015202 BXGD020193 PALMOPLANTAR KERATODERMA AND WOOLLY HAIR
C4015203 BXGD020194 Woolly scalp hair
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4282407 BXGD022423 Sparse and thin eyebrow
C4316909 BXGD022713 Marijuana Use Mental Disorders; Behavior and Behavior Mechanisms
C4540453 BXGD023259 NEPHROTIC SYNDROME, TYPE 16
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein