Showing entry for Large proline-rich protein BAG6


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023748
Protein NameLarge proline-rich protein BAG6
Uniport IdP46379
GeneBAG6
Gene Id7917
DomainBAG6; ubiquitin
Pfam PF12057   PF00240  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007420 brain development
Biological Process GO:0030154 cell differentiation
Biological Process GO:0006325 chromatin organization
Biological Process GO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control
Biological Process GO:0071712 ER-associated misfolded protein catabolic process
Biological Process GO:0002429 immune response-activating cell surface receptor signaling pathway
Biological Process GO:0018393 internal peptidyl-lysine acetylation
Biological Process GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Biological Process GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process GO:0001822 kidney development
Biological Process GO:0030324 lung development
Biological Process GO:1904378 maintenance of unfolded protein involved in ERAD pathway
Biological Process GO:0030101 natural killer cell activation
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Process GO:0045861 negative regulation of proteolysis
Biological Process GO:1904294 positive regulation of ERAD pathway
Biological Process GO:0010498 proteasomal protein catabolic process
Biological Process GO:1904379 protein localization to cytosolic proteasome complex involved in ERAD pathway
Biological Process GO:0050821 protein stabilization
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0045995 regulation of embryonic development
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0007130 synaptonemal complex assembly
Biological Process GO:0071816 tail-anchored membrane protein insertion into ER membrane
Biological Process GO:0030433 ubiquitin-dependent ERAD pathway
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0030544 Hsp70 protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:0051787 misfolded protein binding
molecular function GO:0031593 polyubiquitin modification-dependent protein binding
molecular function GO:0070628 proteasome binding
molecular function GO:0043022 ribosome binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0031625 ubiquitin protein ligase binding
molecular function GO:1990381 ubiquitin-specific protease binding
cellular component GO:0071818 BAT3 complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-9609507 Protein localization
R-HSA-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014518 BXGD000921 Toxic Epidermal Necrolysis Skin and Connective Tissue Diseases; Immune System Diseases; Chemically-Induced Disorders; Stomatognathic Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029410 BXGD002138 Osteoarthritis of hip Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0036391 BXGD002608 Schwartz-Jampel Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0038325 BXGD002745 Stevens-Johnson Syndrome Skin and Connective Tissue Diseases; Immune System Diseases; Chemically-Induced Disorders; Stomatognathic Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0428883 BXGD008639 Diastolic blood pressure
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0871470 BXGD011316 Systolic Pressure
C1305849 BXGD012347 Diastolic blood pressure measurement
C1305855 BXGD012348 Body mass index
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306620 BXGD012371 Systolic blood pressure measurement
C1842937 BXGD014546 AURAL ATRESIA, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3658302 BXGD019260 Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum Skin and Connective Tissue Diseases; Immune System Diseases; Chemically-Induced Disorders; Stomatognathic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein