Showing entry for DNA dC->dU-editing enzyme APOBEC-3H


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023769
Protein NameDNA dC->dU-editing enzyme APOBEC-3H
Uniport IdQ6NTF7
GeneAPOBEC3H
Gene Id164668
DomainNAD1
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.9 Infectious diseases: Viral hsa05170 Human immunodeficiency virus 1 infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016554 cytidine to uridine editing
Biological Process GO:0051607 defense response to virus
Biological Process GO:0070383 DNA cytosine deamination
Biological Process GO:0080111 DNA demethylation
Biological Process GO:0045087 innate immune response
Biological Process GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
Biological Process GO:0010529 negative regulation of transposition
Biological Process GO:0048525 negative regulation of viral process
molecular function GO:0004126 cytidine deaminase activity
molecular function GO:0047844 deoxycytidine deaminase activity
molecular function GO:0003723 RNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0000932 P-body
Reactome
Pathway Id Pathway Name
R-HSA-72200 mRNA Editing: C to U Conversion
R-HSA-75072 mRNA Editing
R-HSA-75094 Formation of the Editosome
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0346429 BXGD007828 Multiple malignancy Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C3714514 BXGD019409 Infection Infections
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein