Showing entry for Probable ATP-dependent RNA helicase DDX58


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023798
Protein NameProbable ATP-dependent RNA helicase DDX58
Uniport IdQ6Q899
GeneDdx58
Gene Id230073
DomainCARD_2; Helicase_C; ResIII; RIG-I_C; RIG-I_C-RD
Pfam PF16739   PF00271   PF04851   PF18119   PF11648  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0140374 antiviral innate immune response
Biological Process GO:0071360 cellular response to exogenous dsRNA
Biological Process GO:0051607 defense response to virus
Biological Process GO:0009597 detection of virus
Biological Process GO:0045087 innate immune response
Biological Process GO:0002230 positive regulation of defense response to virus by host
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
Biological Process GO:0032727 positive regulation of interferon-alpha production
Biological Process GO:0032728 positive regulation of interferon-beta production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0002735 positive regulation of myeloid dendritic cell cytokine production
Biological Process GO:0060760 positive regulation of response to cytokine stimulus
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:1904469 positive regulation of tumor necrosis factor secretion
Biological Process GO:0030334 regulation of cell migration
Biological Process GO:0043330 response to exogenous dsRNA
Biological Process GO:0009615 response to virus
Biological Process GO:0039529 RIG-I signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0003725 double-stranded RNA binding
molecular function GO:0042802 identical protein binding
molecular function GO:0003724 RNA helicase activity
molecular function GO:0003727 single-stranded RNA binding
molecular function GO:0031625 ubiquitin protein ligase binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005923 bicellular tight junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005886 plasma membrane
cellular component GO:1990904 ribonucleoprotein complex
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein