Showing entry for Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023894
Protein NamePhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
Uniport IdQ9ES52
GeneInpp5d
Gene Id16331
DomainExo_endo_phos; SH2
Pfam PF03372   PF00017  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0008340 determination of adult lifespan
Biological Process GO:0016064 immunoglobulin mediated immune response
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0050869 negative regulation of B cell activation
Biological Process GO:0030889 negative regulation of B cell proliferation
Biological Process GO:0045779 negative regulation of bone resorption
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0030853 negative regulation of granulocyte differentiation
Biological Process GO:0050777 negative regulation of immune response
Biological Process GO:0032715 negative regulation of interleukin-6 production
Biological Process GO:0045656 negative regulation of monocyte differentiation
Biological Process GO:0045659 negative regulation of neutrophil differentiation
Biological Process GO:0045671 negative regulation of osteoclast differentiation
Biological Process GO:0009968 negative regulation of signal transduction
Biological Process GO:0046856 phosphatidylinositol dephosphorylation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0045579 positive regulation of B cell differentiation
Biological Process GO:0045648 positive regulation of erythrocyte differentiation
Biological Process GO:0045621 positive regulation of lymphocyte differentiation
molecular function GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
molecular function GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity
molecular function GO:0030487 inositol-4,5-bisphosphate 5-phosphatase activity
molecular function GO:0004445 inositol-polyphosphate 5-phosphatase activity
molecular function GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
molecular function GO:0034594 phosphatidylinositol trisphosphate phosphatase activity
molecular function GO:0051425 PTB domain binding
molecular function GO:0017124 SH3 domain binding
cellular component GO:0005884 actin filament
cellular component GO:0030863 cortical cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004266 2-Propanol 60.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein