protein

Showing entry for SPRY domain-containing SOCS box protein 4

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT023898
Protein Name	SPRY domain-containing SOCS box protein 4
Uniport Id	Q96A44
Gene	SPSB4
Gene Id	92369
Domain	SOCS_box; SPRY
Pfam	PF07525 PF00622
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0035556	intracellular signal transduction
Biological Process	GO:1902916	positive regulation of protein polyubiquitination
Biological Process	GO:0043687	post-translational protein modification
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process	GO:0016567	protein ubiquitination
Biological Process	GO:0042752	regulation of circadian rhythm
Biological Process	GO:0048511	rhythmic process
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process
molecular function	GO:1990756	ubiquitin ligase-substrate adaptor activity
cellular component	GO:0005829	cytosol
cellular component	GO:0019005	SCF ubiquitin ligase complex

Reactome

Pathway Id	Pathway Name
R-HSA-1280218	Adaptive Immune System
R-HSA-168256	Immune System
R-HSA-392499	Metabolism of proteins
R-HSA-597592	Post-translational protein modification
R-HSA-8951664	Neddylation
R-HSA-983168	Antigen processing: Ubiquitination & Proteasome degradation
R-HSA-983169	Class I MHC mediated antigen processing & presentation

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0023893	BXGD001716	Liver Cirrhosis, Experimental	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0038454	BXGD002760	Cerebrovascular accident	Nervous System Diseases; Cardiovascular Diseases
C0041696	BXGD002932	Unipolar Depression	Mental Disorders
C0525045	BXGD009255	Mood Disorders	Mental Disorders
C1269683	BXGD012001	Major Depressive Disorder	Mental Disorders

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0003705	Chloride		35.45
BXGC0049447	acetate		59.01

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}