Showing entry for Dimethyladenosine transferase 2, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023970
Protein NameDimethyladenosine transferase 2, mitochondrial
Uniport IdQ9H5Q4
GeneTFB2M
Gene Id64216
DomainRrnD
Pfam PF00398  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006390 mitochondrial transcription
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0031167 rRNA methylation
Biological Process GO:0006391 transcription initiation from mitochondrial promoter
molecular function GO:0034246 mitochondrial sequence-specific DNA-binding transcription factor activity
molecular function GO:0003723 RNA binding
molecular function GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity
molecular function GO:0003712 transcription coregulator activity
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0042645 mitochondrial nucleoid
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-1592230 Mitochondrial biogenesis
R-HSA-163282 Mitochondrial transcription initiation
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis
R-HSA-74160 Gene expression (Transcription)
R-HSA-75944 Transcription from mitochondrial promoters
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004114 BXGD000255 Astrocytoma Neoplasms
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0338508 BXGD007196 Optic Atrophy 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Nervous System Diseases
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein