Showing entry for Kelch-like protein 20



                       
General Target Information
BXGT IdBXGT024117
Protein NameKelch-like protein 20
Uniport IdQ9Y2M5
GeneKLHL20
Gene Id27252
DomainBACK; BTB; Kelch_1
Pfam PF07707   PF00651   PF01344  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007010 cytoskeleton organization
Biological Process GO:0006895 Golgi to endosome transport
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043687 post-translational protein modification
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:1990390 protein K33-linked ubiquitination
Biological Process GO:0015031 protein transport
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0035455 response to interferon-alpha
molecular function GO:0003779 actin binding
molecular function GO:0019964 interferon-gamma binding
molecular function GO:0004842 ubiquitin-protein transferase activity
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0030424 axon
cellular component GO:0031463 Cul3-RING ubiquitin ligase complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005794 Golgi apparatus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0016605 PML body
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
R-HSA-1280218 Adaptive Immune System
R-HSA-168256 Immune System
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
R-HSA-8951664 Neddylation
R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation
R-HSA-983169 Class I MHC mediated antigen processing & presentation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein