Showing entry for Mucolipin-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024225
Protein NameMucolipin-2
Uniport IdQ8IZK6
GeneMCOLN2
Gene Id255231
DomainPKD_channel
Pfam PF08016  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0045087 innate immune response
Biological Process GO:1905517 macrophage migration
Biological Process GO:1990266 neutrophil migration
Biological Process GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production
Biological Process GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production
Biological Process GO:0071642 positive regulation of macrophage inflammatory protein 1 alpha production
Biological Process GO:0071639 positive regulation of monocyte chemotactic protein-1 production
Biological Process GO:0015031 protein transport
molecular function GO:0042802 identical protein binding
molecular function GO:0072345 NAADP-sensitive calcium-release channel activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0031902 late endosome membrane
cellular component GO:0005764 lysosome
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0055038 recycling endosome membrane
Reactome
Pathway Id Pathway Name
R-HSA-2672351 Stimuli-sensing channels
R-HSA-3295583 TRP channels
R-HSA-382551 Transport of small molecules
R-HSA-983712 Ion channel transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0042769 BXGD002999 Virus Diseases Infections
C0085078 BXGD003118 Lysosomal Storage Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0238286 BXGD004904 Mucolipidosis Type IV Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704230 BXGD013533 Grade I Astrocytoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002591 Potassium 39.1
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein