Showing entry for Tyrosine-protein phosphatase non-receptor type 14


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024385
Protein NameTyrosine-protein phosphatase non-receptor type 14
Uniport IdQ15678
GenePTPN14
Gene Id5784
DomainFERM_C; FERM_M; FERM_N; Y_phosphatase
Pfam PF09380   PF00373   PF09379   PF00102  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071345 cellular response to cytokine stimulus
Biological Process GO:0001946 lymphangiogenesis
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0006470 protein dephosphorylation
Biological Process GO:0046825 regulation of protein export from nucleus
molecular function GO:0004725 protein tyrosine phosphatase activity
molecular function GO:0030971 receptor tyrosine kinase binding
molecular function GO:0003712 transcription coregulator activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-446652 Interleukin-1 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-9008059 Interleukin-37 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003857 BXGD000228 Congenital arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0005612 BXGD000317 Birth Weight Pathological Conditions, Signs and Symptoms
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008297 BXGD000522 Choanal Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0014772 BXGD000948 Red Blood Cell Count measurement
C0017636 BXGD001131 Glioblastoma Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024236 BXGD001752 Lymphedema Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0031039 BXGD002274 Pericardial effusion Cardiovascular Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0039445 BXGD002810 Hereditary hemorrhagic telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0155675 BXGD003808 Pulmonary Arteriovenous Fistulas Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0241790 BXGD005114 Congenital pulmonary arteriovenous malformation Respiratory Tract Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1368275 BXGD012897 Pigmented Basal Cell Carcinoma Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1857690 BXGD015737 Pulmonary arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3150875 BXGD018344 CHOANAL ATRESIA AND LYMPHEDEMA
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0006368 Formic acid 46.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein