Showing entry for Heat shock factor protein 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024442
Protein NameHeat shock factor protein 4
Uniport IdQ9ULV5
GeneHSF4
Gene Id3299
DomainHSF_DNA-bind
Pfam PF00447  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043010 camera-type eye development
Biological Process GO:0048468 cell development
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0033169 histone H3-K9 demethylation
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0045597 positive regulation of cell differentiation
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress
Biological Process GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress
Biological Process GO:0007601 visual perception
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0042802 identical protein binding
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
cellular component GO:0042025 host cell nucleus
cellular component GO:0000790 nuclear chromatin
cellular component GO:0016607 nuclear speck
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001857 BXGD000085 AIDS related complex Infections; Immune System Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009691 BXGD000622 Congenital cataract Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Nervous System Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0036646 BXGD002627 Age-related cataract Eye Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0158551 BXGD003890 Embryonal nuclear cataract (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266537 BXGD005688 Congenital lamellar cataract Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266539 BXGD005689 Congenital total cataract Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0392557 BXGD008056 Nuclear cataract Eye Diseases
C0521158 BXGD009130 Recurrent tumor
C0521707 BXGD009166 Bilateral cataracts (disorder) Eye Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0858617 BXGD011183 Posterior subcapsular cataract Eye Diseases
C1112705 BXGD011681 Nuclear non-senile cataract Eye Diseases
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1833118 BXGD013897 Cataract, Pulverulent Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1855179 BXGD015468 CATARACT, ANTERIOR POLAR Eye Diseases
C1861821 BXGD016076 CATARACT, MARNER TYPE Eye Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3888417 BXGD019970 CATARACT 5, MULTIPLE TYPES
C4290046 BXGD022507 trachomatis
C4524038 BXGD023085 Thoracic myelopathy
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002722 Nitrate 62
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein