protein

Showing entry for Geranylgeranyl transferase type-2 subunit beta

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT024444
Protein Name	Geranylgeranyl transferase type-2 subunit beta
Uniport Id	P53611
Gene	RABGGTB
Gene Id	5876
Domain	Prenyltrans
Pfam	PF00432
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006464	cellular protein modification process
Biological Process	GO:0043687	post-translational protein modification
Biological Process	GO:0018344	protein geranylgeranylation
Biological Process	GO:0018342	protein prenylation
Biological Process	GO:0042981	regulation of apoptotic process
Biological Process	GO:0007601	visual perception
molecular function	GO:0004663	Rab geranylgeranyltransferase activity
molecular function	GO:0017137	Rab GTPase binding
molecular function	GO:0008270	zinc ion binding
cellular component	GO:0005829	cytosol
cellular component	GO:0005886	plasma membrane
cellular component	GO:0005968	Rab-protein geranylgeranyltransferase complex

Reactome

Pathway Id	Pathway Name
R-HSA-212436	Generic Transcription Pathway
R-HSA-3700989	Transcriptional Regulation by TP53
R-HSA-392499	Metabolism of proteins
R-HSA-5633008	TP53 Regulates Transcription of Cell Death Genes
R-HSA-597592	Post-translational protein modification
R-HSA-6803205	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
R-HSA-73857	RNA Polymerase II Transcription
R-HSA-74160	Gene expression (Transcription)
R-HSA-8873719	RAB geranylgeranylation

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0026769	BXGD001930	Multiple Sclerosis	Immune System Diseases; Nervous System Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000696	Tartaric acid		150.09
BXGC0002588	Magnesium		24.31
BXGC0006368	Formic acid		46.03
BXGC0037687	(4S)-2-methylpentane-2,4-diol		118.1

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}