Showing entry for Nuclear protein localization protein 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024550
Protein NameNuclear protein localization protein 4
Uniport IdP33755
GeneNPL4
Gene Id852468
DomainNPL4; zf-NPL4
Pfam PF05021   PF05020  
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071629 cytoplasm protein quality control by the ubiquitin-proteasome system
Biological Process GO:0006274 DNA replication termination
Biological Process GO:0071712 ER-associated misfolded protein catabolic process
Biological Process GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process
Biological Process GO:0051228 mitotic spindle disassembly
Biological Process GO:0051028 mRNA transport
Biological Process GO:0051974 negative regulation of telomerase activity
Biological Process GO:0070651 nonfunctional rRNA decay
Biological Process GO:1900182 positive regulation of protein localization to nucleus
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0072665 protein localization to vacuole
Biological Process GO:0030970 retrograde protein transport, ER to cytosol
Biological Process GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process
Biological Process GO:0030433 ubiquitin-dependent ERAD pathway
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0043130 ubiquitin binding
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0036266 Cdc48p-Npl4p-Vms1p AAA ATPase complex
cellular component GO:0005737 cytoplasm
cellular component GO:0000837 Doa10p ubiquitin ligase complex
cellular component GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex
cellular component GO:0031965 nuclear membrane
cellular component GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0030894 replisome
cellular component GO:1990112 RQC complex
cellular component GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein