Showing entry for Phospholipid-transporting ATPase IA


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024600
Protein NamePhospholipid-transporting ATPase IA
Uniport IdQ9Y2Q0
GeneATP8A1
Gene Id10396
DomainCation_ATPase; E1-E2_ATPase; PhoLip_ATPase_C; PhoLip_ATPase_N
Pfam PF16212   PF16209  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0007612 learning
Biological Process GO:0006869 lipid transport
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0045332 phospholipid translocation
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0061092 positive regulation of phospholipid translocation
Biological Process GO:0055085 transmembrane transport
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0016887 ATPase activity
molecular function GO:0019829 ATPase-coupled cation transmembrane transporter activity
molecular function GO:0140326 ATPase-coupled intramembrane lipid transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0140327 flippase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0022857 transmembrane transporter activity
cellular component GO:0035577 azurophil granule membrane
cellular component GO:0042584 chromaffin granule membrane
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0070062 extracellular exosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0035579 specific granule membrane
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-382551 Transport of small molecules
R-HSA-6798695 Neutrophil degranulation
R-HSA-936837 Ion transport by P-type ATPases
R-HSA-983712 Ion channel transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0162635 BXGD003964 Angelman Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0524957 BXGD009252 Corneal Topography
C1269955 BXGD012005 Tumor Cell Invasion
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C2699541 BXGD017461 Cytokine Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein