Showing entry for Aquaporin-7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024716
Protein NameAquaporin-7
Uniport IdO14520
GeneAQP7
Gene Id364
DomainMIP
Pfam PF00230  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa03320 PPAR signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04923 Regulation of lipolysis in adipocytes
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015793 glycerol transport
Biological Process GO:0006833 water transport
molecular function GO:0015254 glycerol channel activity
molecular function GO:0015204 urea transmembrane transporter activity
molecular function GO:0015250 water channel activity
cellular component GO:0005911 cell-cell junction
cellular component GO:0005938 cell cortex
cellular component GO:0005737 cytoplasm
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005811 lipid droplet
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-432030 Transport of glycerol from adipocytes to the liver by Aquaporins
R-HSA-432047 Passive transport by Aquaporins
R-HSA-445717 Aquaporin-mediated transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001925 BXGD000090 Albuminuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028756 BXGD002083 Obesity, Morbid Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0206682 BXGD004237 Follicular thyroid carcinoma Neoplasms
C0267990 BXGD005800 Adult-onset obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0341306 BXGD007401 Microvillus inclusion disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1306341 BXGD012360 Mental handicap
C2362324 BXGD017091 Pediatric Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2931689 BXGD018049 Dystrophia myotonica 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C3280715 BXGD018857 GLYCEROL QUANTITATIVE TRAIT LOCUS
C3495840 BXGD019007 Pancreatic steatosis
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein