Showing entry for Endonuclease G, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024789
Protein NameEndonuclease G, mitochondrial
Uniport IdO08600
GeneEndog
Gene Id13804
DomainEndonuclease_NS
Pfam PF01223  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0006309 apoptotic DNA fragmentation
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0006308 DNA catabolic process
Biological Process GO:0000737 DNA catabolic process, endonucleolytic
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0036475 neuron death in response to oxidative stress
Biological Process GO:1902512 positive regulation of apoptotic DNA fragmentation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0032355 response to estradiol
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0034612 response to tumor necrosis factor
molecular function GO:0004536 deoxyribonuclease activity
molecular function GO:0004519 endonuclease activity
molecular function GO:0004521 endoribonuclease activity
molecular function GO:0046872 metal ion binding
molecular function GO:0004518 nuclease activity
molecular function GO:0003676 nucleic acid binding
molecular function GO:0000014 single-stranded DNA endodeoxyribonuclease activity
cellular component GO:0005829 cytosol
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0004266 2-Propanol 60.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein