Showing entry for Histone acetyltransferase KAT7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024818
Protein NameHistone acetyltransferase KAT7
Uniport IdO95251
GeneKAT7
Gene Id11143
DomainMOZ_SAS; zf-C2HC; zf-MYST
Pfam PF01853   PF01530   PF17772  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006281 DNA repair
Biological Process GO:0006260 DNA replication
Biological Process GO:0043966 histone H3 acetylation
Biological Process GO:0044154 histone H3-K14 acetylation
Biological Process GO:0043967 histone H4 acetylation
Biological Process GO:0043983 histone H4-K12 acetylation
Biological Process GO:0043981 histone H4-K5 acetylation
Biological Process GO:0043982 histone H4-K8 acetylation
Biological Process GO:0018393 internal peptidyl-lysine acetylation
Biological Process GO:0001779 natural killer cell differentiation
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0045740 positive regulation of DNA replication
Biological Process GO:0032786 positive regulation of DNA-templated transcription, elongation
Biological Process GO:0045648 positive regulation of erythrocyte differentiation
Biological Process GO:1902035 positive regulation of hematopoietic stem cell proliferation
Biological Process GO:0090240 positive regulation of histone H4 acetylation
Biological Process GO:1900182 positive regulation of protein localization to nucleus
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0030174 regulation of DNA-dependent DNA replication initiation
Biological Process GO:2000819 regulation of nucleotide-excision repair
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0072716 response to actinomycin D
Biological Process GO:0072739 response to anisomycin
Biological Process GO:0072720 response to dithiothreitol
Biological Process GO:0072710 response to hydroxyurea
Biological Process GO:0072708 response to sorbitol
Biological Process GO:0031098 stress-activated protein kinase signaling cascade
molecular function GO:0003688 DNA replication origin binding
molecular function GO:0010485 H4 histone acetyltransferase activity
molecular function GO:0004402 histone acetyltransferase activity
molecular function GO:0042393 histone binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005694 chromosome
cellular component GO:0000775 chromosome, centromeric region
cellular component GO:0005829 cytosol
cellular component GO:0000123 histone acetyltransferase complex
cellular component GO:0036409 histone H3-K14 acetyltransferase complex
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0032777 Piccolo NuA4 histone acetyltransferase complex
cellular component GO:0090734 site of DNA damage
Reactome
Pathway Id Pathway Name
R-HSA-3214847 HATs acetylate histones
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-4839726 Chromatin organization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023480 BXGD001664 Leukemia, Myelomonocytic, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023518 BXGD001677 Leukocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0039585 BXGD002821 Androgen-Insensitivity Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0043346 BXGD003043 Xeroderma Pigmentosum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0349639 BXGD007943 Juvenile Myelomonocytic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0424166 BXGD008521 Social Anxiety Behavior and Behavior Mechanisms
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0730328 BXGD009959 Central Serous Chorioretinopathy Eye Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein