Showing entry for Bcl-2 homologous antagonist/killer


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024828
Protein NameBcl-2 homologous antagonist/killer
Uniport IdO08734
GeneBak1
Gene Id12018
DomainBcl-2
Pfam PF00452  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097202 activation of cysteine-type endopeptidase activity
Biological Process GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
Biological Process GO:0007568 aging
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0006915 apoptotic process
Biological Process GO:1902262 apoptotic process involved in blood vessel morphogenesis
Biological Process GO:0097190 apoptotic signaling pathway
Biological Process GO:0001783 B cell apoptotic process
Biological Process GO:0001782 B cell homeostasis
Biological Process GO:0002352 B cell negative selection
Biological Process GO:0001974 blood vessel remodeling
Biological Process GO:0007420 brain development
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0071260 cellular response to mechanical stimulus
Biological Process GO:0034644 cellular response to UV
Biological Process GO:0031018 endocrine pancreas development
Biological Process GO:0010248 establishment or maintenance of transmembrane electrochemical gradient
Biological Process GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
Biological Process GO:0044346 fibroblast apoptotic process
Biological Process GO:0048872 homeostasis of number of cells
Biological Process GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process GO:0001776 leukocyte homeostasis
Biological Process GO:0035108 limb morphogenesis
Biological Process GO:0008053 mitochondrial fusion
Biological Process GO:0002262 myeloid cell homeostasis
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0033137 negative regulation of peptidyl-serine phosphorylation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0010524 positive regulation of calcium ion transport into cytosol
Biological Process GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response
Biological Process GO:0031334 positive regulation of protein-containing complex assembly
Biological Process GO:0045862 positive regulation of proteolysis
Biological Process GO:0090200 positive regulation of release of cytochrome c from mitochondria
Biological Process GO:0048597 post-embryonic camera-type eye morphogenesis
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0046902 regulation of mitochondrial membrane permeability
Biological Process GO:0051881 regulation of mitochondrial membrane potential
Biological Process GO:0001836 release of cytochrome c from mitochondria
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0009620 response to fungus
Biological Process GO:0010332 response to gamma radiation
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0010046 response to mycotoxin
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0010225 response to UV-C
Biological Process GO:0070242 thymocyte apoptotic process
Biological Process GO:0060068 vagina development
Biological Process GO:0016032 viral process
molecular function GO:0051400 BH domain binding
molecular function GO:0051087 chaperone binding
molecular function GO:0031072 heat shock protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:0044325 ion channel binding
molecular function GO:0046872 metal ion binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0097145 BAK complex
cellular component GO:0097136 Bcl-2 family protein complex
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0031307 integral component of mitochondrial outer membrane
cellular component GO:0016020 membrane
cellular component GO:0031966 mitochondrial membrane
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0046930 pore complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006368 Formic acid 46.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein