Showing entry for Septin-12


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024860
Protein NameSeptin-12
Uniport IdQ8IYM1
GeneSEPTIN12
Gene Id124404
DomainSeptin
Pfam PF00735  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05100 Bacterial invasion of epithelial cells
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030154 cell differentiation
Biological Process GO:0034613 cellular protein localization
Biological Process GO:0061640 cytoskeleton-dependent cytokinesis
Biological Process GO:0030317 flagellated sperm motility
Biological Process GO:0007283 spermatogenesis
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0060090 molecular adaptor activity
molecular function GO:0035091 phosphatidylinositol binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0032153 cell division site
cellular component GO:0032154 cleavage furrow
cellular component GO:0015630 microtubule cytoskeleton
cellular component GO:0030496 midbody
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0031105 septin complex
cellular component GO:0005940 septin ring
cellular component GO:0097227 sperm annulus
cellular component GO:0005819 spindle
cellular component GO:0001725 stress fiber
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004509 BXGD000275 Azoospermia Male Urogenital Diseases
C0021359 BXGD001498 Infertility Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0028960 BXGD002101 Oligospermia Male Urogenital Diseases
C0403823 BXGD008315 Asthenozoospermia Male Urogenital Diseases
C0403824 BXGD008316 Teratozoospermia Male Urogenital Diseases
C3164407 BXGD018528 Oligoasthenozoospermia
C3553793 BXGD019190 SPERMATOGENIC FAILURE 10
C4021107 BXGD020557 Non-obstructive azoospermia Male Urogenital Diseases
C4021812 BXGD020798 Abnormality of the head
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein