Showing entry for NAD(+) hydrolase SARM1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025034
Protein NameNAD(+) hydrolase SARM1
Uniport IdQ6SZW1
GeneSARM1
Gene Id23098
DomainSAM_2; TIR_2
Pfam PF07647   PF13676  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045087 innate immune response
Biological Process GO:0019677 NAD catabolic process
Biological Process GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0048814 regulation of dendrite morphogenesis
Biological Process GO:1901214 regulation of neuron death
Biological Process GO:0048678 response to axon injury
Biological Process GO:0009749 response to glucose
Biological Process GO:0007165 signal transduction
molecular function GO:0042802 identical protein binding
molecular function GO:0050135 NAD(P)+ nucleosidase activity
molecular function GO:0003953 NAD+ nucleosidase activity
molecular function GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
molecular function GO:0035591 signaling adaptor activity
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0031315 extrinsic component of mitochondrial outer membrane
cellular component GO:0005874 microtubule
cellular component GO:0005739 mitochondrion
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0035235 BXGD002519 Respiratory Syncytial Virus Infections Infections
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0042769 BXGD002999 Virus Diseases Infections
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0085933 BXGD003259 Infections, Bunyavirus Infections
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0342705 BXGD007531 Folate Malabsorption, Hereditary Digestive System Diseases; Nutritional and Metabolic Diseases
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1262886 BXGD011887 Osteoprotegerin test
C1842675 BXGD014528 AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder)
C1862939 BXGD016144 AMYOTROPHIC LATERAL SCLEROSIS 1 Nutritional and Metabolic Diseases; Nervous System Diseases
C1862941 BXGD016145 Amyotrophic Lateral Sclerosis, Sporadic Nutritional and Metabolic Diseases; Nervous System Diseases
C2697786 BXGD017439 Interleukin 5 Measurement
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C3542025 BXGD019103 AMYOTROPHIC LATERAL SCLEROSIS 1, AUTOSOMAL RECESSIVE
C3873567 BXGD019863 Peripheral neuropathy due to and following chemotherapy Nervous System Diseases
C4024896 BXGD021461 Motor neuron atrophy
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0038991 Selenomethionine 197
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein