Showing entry for Endonuclease V


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025150
Protein NameEndonuclease V
Uniport IdQ8N8Q3
GeneENDOV
Gene Id284131
DomainEndonuclease_5
Pfam PF04493  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006281 DNA repair
molecular function GO:0003677 DNA binding
molecular function GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
molecular function GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters
molecular function GO:0000287 magnesium ion binding
molecular function GO:0003727 single-stranded RNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0010494 cytoplasmic stress granule
cellular component GO:0005730 nucleolus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0009207 BXGD000593 Cockayne Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0011848 BXGD000750 Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0022602 BXGD001564 Actinic keratosis Neoplasms; Skin and Connective Tissue Diseases
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0043346 BXGD003043 Xeroderma Pigmentosum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein