Showing entry for Coatomer subunit alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025196
Protein NameCoatomer subunit alpha
Uniport IdP53621
GeneCOPA
Gene Id1314
DomainANAPC4_WD40; Coatomer_WDAD; COPI_C; WD40
Pfam PF12894   PF04053   PF06957   PF00400  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0006891 intra-Golgi vesicle-mediated transport
Biological Process GO:0030157 pancreatic juice secretion
Biological Process GO:0099612 protein localization to axon
Biological Process GO:1902463 protein localization to cell leading edge
Biological Process GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
molecular function GO:0005179 hormone activity
molecular function GO:0003729 mRNA binding
molecular function GO:0005198 structural molecule activity
cellular component GO:0030126 COPI vesicle coat
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0005615 extracellular space
cellular component GO:0000139 Golgi membrane
cellular component GO:0030426 growth cone
cellular component GO:0016020 membrane
cellular component GO:0030133 transport vesicle
Reactome
Pathway Id Pathway Name
R-HSA-199977 ER to Golgi Anterograde Transport
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-6807878 COPI-mediated anterograde transport
R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic
R-HSA-8856688 Golgi-to-ER retrograde transport
R-HSA-948021 Transport to the Golgi and subsequent modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0010200 BXGD000653 Coughing Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0018923 BXGD001248 Hemangiosarcoma Neoplasms
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151632 BXGD003450 ESR raised
C0151701 BXGD003462 Pulmonary hemorrhage Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0162323 BXGD003937 Polyarthritis Musculoskeletal Diseases
C0206061 BXGD004147 Pneumonia, Interstitial Respiratory Tract Diseases
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0231835 BXGD004527 Tachypnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0278592 BXGD006544 Adult Angiosarcoma Neoplasms
C0279988 BXGD006707 Childhood Angiosarcoma Neoplasms
C0403416 BXGD008282 Idiopathic crescentic glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0475713 BXGD008967 Perinatal pulmonary hemorrhage
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3860213 BXGD019844 Autoinflammatory disorder
C4225334 BXGD022227 AUTOIMMUNE INTERSTITIAL LUNG, JOINT, AND KIDNEY DISEASE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000696 Tartaric acid 150.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein