Showing entry for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025231
Protein Name1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
Uniport IdQ99P84
GenePlce1
Gene Id114633
DomainC2; PI-PLC-X; PI-PLC-Y; RA; RasGEF
Pfam PF00168   PF00388   PF00387   PF00788   PF00617  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0006651 diacylglycerol biosynthetic process
Biological Process GO:0007173 epidermal growth factor receptor signaling pathway
Biological Process GO:0032835 glomerulus development
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0016042 lipid catabolic process
Biological Process GO:0048015 phosphatidylinositol-mediated signaling
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0010592 positive regulation of lamellipodium assembly
Biological Process GO:0007265 Ras protein signal transduction
Biological Process GO:0008277 regulation of G protein-coupled receptor signaling pathway
Biological Process GO:0045859 regulation of protein kinase activity
Biological Process GO:0046578 regulation of Ras protein signal transduction
molecular function GO:0019899 enzyme binding
molecular function GO:0005085 guanyl-nucleotide exchange factor activity
molecular function GO:0046872 metal ion binding
molecular function GO:0004435 phosphatidylinositol phospholipase C activity
molecular function GO:0004629 phospholipase C activity
molecular function GO:0017016 Ras GTPase binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0000139 Golgi membrane
cellular component GO:0030027 lamellipodium
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein