Showing entry for Integrin alpha-M


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025441
Protein NameIntegrin alpha-M
Uniport IdP05555
GeneItgam
Gene Id
DomainFG-GAP; Integrin_alpha; Integrin_alpha2; VWA
Pfam PF01839   PF00357   PF08441   PF00092  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050798 activated T cell proliferation
Biological Process GO:0097242 amyloid-beta clearance
Biological Process GO:0097190 apoptotic signaling pathway
Biological Process GO:0007155 cell adhesion
Biological Process GO:0098609 cell-cell adhesion
Biological Process GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling
Biological Process GO:0045123 cellular extravasation
Biological Process GO:0150062 complement-mediated synapse pruning
Biological Process GO:0030900 forebrain development
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0061756 leukocyte adhesion to vascular endothelial cell
Biological Process GO:0007159 leukocyte cell-cell adhesion
Biological Process GO:0002523 leukocyte migration involved in inflammatory response
Biological Process GO:0014005 microglia development
Biological Process GO:0001774 microglial cell activation
Biological Process GO:0045963 negative regulation of dopamine metabolic process
Biological Process GO:0001781 neutrophil apoptotic process
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0006909 phagocytosis
Biological Process GO:0006911 phagocytosis, engulfment
Biological Process GO:0110090 positive regulation of hippocampal neuron apoptotic process
Biological Process GO:0060376 positive regulation of mast cell differentiation
Biological Process GO:1904151 positive regulation of microglial cell mediated cytotoxicity
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0043315 positive regulation of neutrophil degranulation
Biological Process GO:1903223 positive regulation of oxidative stress-induced neuron death
Biological Process GO:2000363 positive regulation of prostaglandin-E synthase activity
Biological Process GO:0090314 positive regulation of protein targeting to membrane
Biological Process GO:0032930 positive regulation of superoxide anion generation
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0150064 vertebrate eye-specific patterning
molecular function GO:0038024 cargo receptor activity
molecular function GO:0001851 complement component C3b binding
molecular function GO:0031072 heat shock protein binding
molecular function GO:0043395 heparan sulfate proteoglycan binding
molecular function GO:0008201 heparin binding
molecular function GO:0046872 metal ion binding
molecular function GO:0001846 opsonin binding
molecular function GO:0044877 protein-containing complex binding
cellular component GO:0009986 cell surface
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0034688 integrin alphaM-beta2 complex
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0044853 plasma membrane raft
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000441 Dimethyl sulfoxide 78.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein