Showing entry for Twinfilin-1



                       
General Target Information
BXGT IdBXGT025477
Protein NameTwinfilin-1
Uniport IdQ91YR1
GeneTwf1
Gene Id19230
DomainCofilin_ADF
Pfam PF00241  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030042 actin filament depolymerization
Biological Process GO:0051016 barbed-end actin filament capping
Biological Process GO:0030837 negative regulation of actin filament polymerization
Biological Process GO:0010613 positive regulation of cardiac muscle hypertrophy
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:0043538 regulation of actin phosphorylation
Biological Process GO:0010591 regulation of lamellipodium assembly
Biological Process GO:0042989 sequestering of actin monomers
molecular function GO:0003779 actin binding
molecular function GO:0051015 actin filament binding
molecular function GO:0003785 actin monomer binding
molecular function GO:0005524 ATP binding
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0004713 protein tyrosine kinase activity
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005884 actin filament
cellular component GO:0005911 cell-cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030175 filopodium
cellular component GO:0030016 myofibril
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein